OMIA:002697-9925 : Hair morphology, EDAR-related in Capra hircus (goat)

Categories: Integument (skin) phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 604095 (gene) , 612630 (trait)

Mendelian trait/disorder: yes

Considered a defect: no

Key variant known: no

Species-specific description: This phene includes references to studies involving gene edited or genetically modified organisms (GMO).

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: Cashmere (Goat) (VBO_0000745).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
EDAR ectodysplasin A receptor Capra hircus 11 NC_030818.1 (44156593..44209372) EDAR Homologene, Ensembl , NCBI gene

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002697-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Gao, G.Z., Hao, F., Zhu, L., Jiang, G.Q., Yan, W., Liu, J., Liu, D.J. :
Combination of transcriptomics and proteomics reveals differentially expressed genes and proteins in the skin of EDAR gene-targeted and wildtype Cashmere goats. Animals (Basel) 13, 2023. Pubmed reference: 37174489. DOI: 10.3390/ani13091452.
2018 Hao, F., Yan, W., Li, X., Wang, H., Wang, Y., Hu, X., Liu, X., Liang, H., Liu, D. :
Generation of Cashmere goats carrying an EDAR gene mutant using CRISPR-Cas9-mediated genome editing. Int J Biol Sci 14:427-436, 2018. Pubmed reference: 29725264. DOI: 10.7150/ijbs.23890.

Edit History

  • Created by Imke Tammen2 on 15 May 2023
  • Changed by Imke Tammen2 on 15 May 2023
  • Changed by Imke Tammen2 on 18 Dec 2023