OMIA:002752-8090 : Cardiac defects, MYRF-related in Oryzias latipes (Japanese medaka) |
Categories: Cardiovascular system phene
Links to possible relevant human trait(s) and/or gene(s) in OMIM: 618280 (trait) , 608329 (gene)
Mendelian trait/disorder: yes
Disease-related: yes
Key variant known: no
Species-specific description: This phene includes references to studies involving gene edited or genetically modified organisms (GMO).
Genetic engineering:
Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| myrfl | myelin regulatory factor-like | Oryzias latipes | 23 | NC_019881.1 (24122469..24126976) | myrfl | Homologene, Ensembl , NCBI gene |
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002752-8090: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2023 | Doering, L., Cornean, A., Thumberger, T., Benjaminsen, J., Wittbrodt, B., Kellner, T., Hammouda, O.T., Gorenflo, M., Wittbrodt, J., Gierten, J. : |
| CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease. Dis Model Mech 16:dmm049811, 2023. Pubmed reference: 37584388. DOI: 10.1242/dmm.049811. |
Edit History
- Created by Imke Tammen2 on 18 Aug 2023
- Changed by Imke Tammen2 on 18 Aug 2023
- Changed by Imke Tammen2 on 18 Dec 2023