OMIA:002889-7957 : Skin colour, PAX7-related in Carassius auratus (goldfish)

In other species: Leopard gecko

Categories: Pigmentation phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 167410 (gene)

Single-gene trait/disorder: yes

Disease-related: unknown

Key variant known: yes

Year key variant first reported: 2024

Species-specific description: Mouri et al. (2024) used CRISPR/Cas9 genome editing to knockout the pax7a and pax7b genes to create transparent goldfish. Leucophore numbers were reduced in pax7b-/- fish but not in pax7a-/- fish. This study involves gene edited or genetically modified organisms (GMO).

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
pax7b Carassius auratus - no genomic information (-..-) pax7b Ensembl

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:002889-7957: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2024 Mouri, T., Usa, S., Tokumoto, T. :
Pax7 is involved in leucophore formation in goldfish and gene knockout improves the transparency of transparent goldfish. Fish Physiol Biochem 50:1701-1710, 2024. Pubmed reference: 38819758. DOI: 10.1007/s10695-024-01364-z.

Edit History


  • Created by Imke Tammen2 on 07 Sep 2024
  • Changed by Imke Tammen2 on 07 Sep 2024