OMIA:002896-749190 : Skin colour, SCARB1-related in Cyprinus carpio 'color' (Oujiang color common carp) |
Categories: Pigmentation phene
Links to possible relevant human trait(s) and/or gene(s) in OMIM: 601040 (gene)
Mendelian trait/disorder: unknown
Disease-related: no
Species-specific description: Du et al. (2021) "showed that red and white coloration followed typical Mendelian inheritance in color common carp and that red coloration was determined by the carotenoids rather than the pteridine pigments. The two Scarb1 genes might act as a “switch” in the red carotenoid ornamentation in fish by mediating the transport process of carotenoids and thus controlling the formation of red coloration."
Inheritance: Wang et al. (2008) reported the results of an artificial reciprocal cross of whole red (WR) and whole white (WW) body colour fish. The trait followed the typical Mendelian inheritance patterns in the F2 generation (WR:WW ≈ 3:1)
Genetic engineering:
Yes - in addition to the occurrence of natural variants, variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| SCARB1 | Cyprinus carpio 'color' | - | no genomic information (-..-) | SCARB1 | Ensembl |
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:002896-749190: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2024 | Kanika, N.H., Hou, X., Liu, H., Dong, Y., Jun, W., Chenghui, W. : |
| Specific gut microbiome's role in skin pigmentation: insights from SCARB1 mutants in Oujiang color common carp. J Appl Microbiol 135:lxae226, 2024. Pubmed reference: 39243120. DOI: 10.1093/jambio/lxae226. | |
| 2023 | Kanika, N.H., Ke, J., Mandal, R.N., Wang, J., Wang, C. : |
| Comparative transcriptome and metabolome analyses of wild and mutant Oujiang color common carp through editing SCARB1 gene by CRISPR/Cas technology. Aquaculture 577:739901, 2023. DOI: 10.1016/j.aquaculture.2023.739901. | |
| 2021 | Du, J., Chen, H, Mandal, B.K., Wang, J., Shi, Z., Lu, G., Wang, C. : |
| HDL receptor/Scavenger receptor B1-Scarb1 and Scarb1-like mediate the carotenoid-based red coloration in fish. Aquaculture 545:737208, 2021. DOI: 10.1016/j.aquaculture.2021.737208. | |
| 2008 | Wang, C.H., Xiang, S.P., LC, Y.P., Wang J., Pan, Z.Y., He, X.Z. : |
| [Preliminary study on inheritance of red and white color phenotypes in Oujiang color carp, C. carpio var. color] (in Chinese). Shanghai Ocean Uni. 4:402-405, 2008. |
Edit History
- Created by Imke Tammen2 on 09 Sep 2024