OMIA:002982-9313 : Aneuploidy, trisomy, sex chromosome XXY in Notamacropus agilis (Agile wallaby)

In other species: dog , domestic cat , domestic horse , pig , taurine cattle , sheep

Categories: Reproductive system phene , Chromosomal phene

Links to relevant human diseases in MONDO:

Single-gene trait/disorder: unknown

Disease-related: yes

Cross-species summary: This phene includes information about differences of sexual development (DSD) in animals due to XXY trisomy of sex chromosomes. This phenotype is called  Klinefelter syndrome in humans.

Species summary:  [IT thanks Emma Faull for contributions to this entry in September 2025]  

Molecular basis: Watson at al. (1997) reported an agile wallaby with DSD that had a karyotype of 17, XXY. The animal tested  positive for the SRY gene via PCR.

Clinical features: Watson et al. (1997) described an 17-month-old intersex agile wallaby with "a fully developed pouch with four inverted teats" and a penis. 

Contact us

If you notice anything missing or in need of change, please contact us at: [email protected].

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2025). OMIA:002982-9313: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

1997 Watson, C.M., Johnston, P.G., Rodger, K.A., McKenzie, L.M., O'Neill, R.J., Cooper, D.W. :
SRY and karyotypic status of one abnormal and two intersexual marsupials. Reprod Fertil Dev 9:233-41, 1997. Pubmed reference: 9208434. DOI: 10.1071/r96107.

Edit History


  • Created by Imke Tammen2 on 08 Sep 2025