OMIA:003032-9913 : Fatty acid desaturase 3 (Fad3), transgenic in Bos taurus (taurine cattle) |
Categories: Homeostasis / metabolism phene
Single-gene trait/disorder: unknown
Disease-related: no
Species summary: Su et al. (2025) "created fatty acid desaturase 3 (Fad3) transgenic cattle by utilizing CRISPR-Cas9 technology to insert a codon-optimized Fad3 gene sequence into bovine fibroblast cells and employing somatic cell nuclear transfer (SCNT) technology. Gas chromatographic analysis confirmed that the n-3 PUFA (polyunsaturated fatty acid) content in the transgenic cattle was significantly increased, while the ratio of n-6 PUFAs to n-3 PUFAs decreased." This study involves gene edited or genetically modified organisms (GMO).
Genetic engineering:
Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing
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Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2026). OMIA:003032-9913: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2025 | Su, G., Wei, Z., Bai, C., Li, D., Zhao, X., Liu, X., Song, L., Zhang, L., Li, G., Yang, L. : |
| Generation of codon-optimized Fad3 gene transgenic bovine that produce more n-3 polyunsaturated fatty acids. Animals (Basel) 15:93, 2025. Pubmed reference: 39795036. DOI: 10.3390/ani15010093. |
Edit History
- Created by Imke Tammen2 on 06 Jan 2026