Categories: Cardiovascular system phene , Homeostasis / metabolism phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 606368 (gene) , 145750 (trait) , 144650 (trait)

Single-gene trait/disorder: yes

Disease-related: yes

Key variant known: no

Species summary: Zha et al. (2026) "generated and phenotyped APOA5-mutant rabbits using CRISPR/Cas9-mediated targeting of exon 2." This study involves gene edited or genetically modified organisms (GMO).

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: New Zealand White (Rabbit) (VBO_0001269).
Breeds in which the phene or likely causal variants have been documented. If a likely causal variant has been documented, see variant-specific breed information in the variant table. (Breed information may be incomplete).

Associated gene: