You are here: OMIA / Search / dog

Gene IGF1 : insulin-like growth factor 1 (somatomedin C) in Canis lupus familiaris

 See the equivalent entry at NCBI

In other species: chicken , horse

Symbol: IGF1

Synonyms: IGF-I, IGFI, IGFIA

Description: insulin-like growth factor 1 (somatomedin C)

Type of gene: protein-coding

NCBI gene id: 610255

Other designations: insulin-like growth factor I|somatomedin C

Links: Homologene , Ensembl

Genomic location: 15:41930681..41855737 [Chromosome accession NC_051819.1]

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2013 Rimbault, M., Beale, H.C., Schoenebeck, J.J., Hoopes, B.C., Allen, J.J., Kilroy-Glynn, P., Wayne, R.K., Sutter, N.B., Ostrander, E.A. :
Derived variants at six genes explain nearly half of size reduction in dog breeds. Genome Res 23:1985-95, 2013. Pubmed reference: 24026177. DOI: 10.1101/gr.157339.113.
2012 Hoopes, B.C., Rimbault, M., Liebers, D., Ostrander, E.A., Sutter, N.B. :
The insulin-like growth factor 1 receptor (IGF1R) contributes to reduced size in dogs. Mamm Genome 23:780-90, 2012. Pubmed reference: 22903739. DOI: 10.1007/s00335-012-9417-z.
2010 Gray, M.M., Sutter, N.B., Ostrander, E.A., Wayne, R.K. :
The IGF1 small dog haplotype is derived from Middle Eastern grey wolves. BMC Biol 8:16, 2010. Pubmed reference: 20181231. DOI: 10.1186/1741-7007-8-16.
2007 Sutter, N.B., Bustamante, C.D., Chase, K., Gray, M.M., Zhao, K., Zhu, L., Padhukasahasram, B., Karlins, E., Davis, S., Jones, P.G., Quignon, P., Johnson, G.S., Parker, H.G., Fretwell, N., Mosher, D.S., Lawler, D.F., Satyaraj, E., Nordborg, M., Lark, K.G., Wayne, R.K., Ostrander, E.A. :
A single IGF1 allele is a major determinant of small size in dogs. Science 316:112-5, 2007. Pubmed reference: 17412960. DOI: 10.1126/science.1137045.