OMIA 000029-9615 : Alloxan-diabetes in Canis lupus familiaris |
Mendelian trait/disorder:
no
Considered a defect:
yes
Key variant known:
no
Cross-species summary:
Alloxan is an organic compound that causes diabetes mellitus by partial degradation of the beta (β) cells of pancreatic islets, which reduces the quality and quantity of insulin.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 1996 | Matsunaga, T., Okumura, K., Ishizaka, H., Tsunoda, R., Tayama, S., Tabuchi, T., Yasue, H. : | |
| Impairment of coronary blood flow regulation by endothelium-derived nitric oxide in dogs with alloxan-induced diabetes Journal of Cardiovascular Pharmacology 28:60-67, 1996. Pubmed reference: 8797137. | ||
| 1995 | Damge, C., Hillairebuys, D., Puech, R., Hoeltzel, A., Michel, C., Ribes, G. : | |
| Effects of orally administered insulin nanocapsules in normal and diabetic dogs Diabetes Nutrition & Metabolism 8:3-9, 1995. | ||
| 1993 | Rastogi, K.S., Brubaker, P.L., Kawasaki, A., Efendic, S., Vranic, M. : | |
| Increase in Somatostatin to Glucagon Ratio in Islets of Alloxan-Diabetic Dogs - Effect of Insulin-Induced Euglycemia Canadian Journal of Physiology and Pharmacology 71:512-517, 1993. Pubmed reference: 7902197. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Imke Tammen2 on 20 Mar 2022