OMIA:000029-9615 : Alloxan-diabetes in Canis lupus familiaris (dog)

Categories: Homeostasis / metabolism phene

Mendelian trait/disorder: no

Considered a defect: yes

Key variant known: no

Cross-species summary: Alloxan is an organic compound that causes diabetes mellitus by partial degradation of the beta (β) cells of pancreatic islets, which reduces the quality and quantity of insulin.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:000029-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1996 Matsunaga, T., Okumura, K., Ishizaka, H., Tsunoda, R., Tayama, S., Tabuchi, T., Yasue, H. :
Impairment of coronary blood flow regulation by endothelium-derived nitric oxide in dogs with alloxan-induced diabetes Journal of Cardiovascular Pharmacology 28:60-67, 1996. Pubmed reference: 8797137.
1995 Damge, C., Hillairebuys, D., Puech, R., Hoeltzel, A., Michel, C., Ribes, G. :
Effects of orally administered insulin nanocapsules in normal and diabetic dogs Diabetes Nutrition & Metabolism 8:3-9, 1995.
1993 Rastogi, K.S., Brubaker, P.L., Kawasaki, A., Efendic, S., Vranic, M. :
Increase in somatostatin to glucagon ratio in islets of alloxan-diabetic dogs - Effect of insulin-induced euglycemia Can J Physiol Pharmacol 71:512-7, 1993. Pubmed reference: 7902197. DOI: 10.1139/y93-074.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 20 Mar 2022