OMIA 000120-9031 : Blood group system B in Gallus gallus

In other species: cattle , goat , pig , sheep , , aoudad

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Co-Dominant

Considered a defect: no

Key variant known: no

Cross-species summary: Each blood group system consists of a set of blood types, each of which corresponds to a particular antigen (usually a glycoprotein) on the surface of red blood cells. The different types within a system are the result of the action of different alleles at a locus that usually encodes an enzyme that catalyses the creation of the feature of the glycoprotein unique to that type, e.g. the presence of a particular sugar at the end of a short chain of sugars.

Species-specific description: The B blood group system in chickens is also the major histocompatibility complex (MHC) of this species.

Inheritance: Briles et al. (1959) confirmed the existence of four loci (blood group systems), namely A, B, D, and E, with some evidence of tight linkage between A and E.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2011 Chazara, O., Tixier-Boichard, M., Morin, V., Zoorob, R., Bed'hom, B. :
Organisation and diversity of the class II DM region of the chicken MHC. Mol Immunol 48:1263-71, 2011. Pubmed reference: 21481938. DOI: 10.1016/j.molimm.2011.03.009.
Walker, B.A., Hunt, L.G., Sowa, A.K., Skjødt, K., Göbel, T.W., Lehner, P.J., Kaufman, J. :
The dominantly expressed class I molecule of the chicken MHC is explained by coevolution with the polymorphic peptide transporter (TAP) genes. Proc Natl Acad Sci U S A 108:8396-401, 2011. Pubmed reference: 21536896. DOI: 10.1073/pnas.1019496108.
2006 Li, G.Q., Lu, L.Z., Wang, D.Q., Shen, J.D., Tao, Z.R., Zhao, A.Z., Yuan, A.P. :
[Advance in association studies of major histocompatibility complex (MHC) gene polymorphisms with traits of resistance against infectious disease in chickens]. Yi Chuan 28:893-8, 2006. Pubmed reference: 16825180.
2004 Miller, M.M., Bacon, L.D., Hala, K., Hunt, H.D., Ewald, S.J., Kaufman, J., Zoorob, R., Briles, W.E. :
2004 Nomenclature for the chicken major histocompatibility (B and Y) complex. Immunogenetics 56:261-79, 2004. Pubmed reference: 15257423. DOI: 10.1007/s00251-004-0682-1.
Taylor, R.L. :
Major histocompatibility (B) complex control of responses against Rous sarcomas. Poult Sci 83:638-49, 2004. Pubmed reference: 15109061.
2000 Kaufman, J. :
The simple chicken major histocompatibility complex: life and death in the face of pathogens and vaccines. Philos Trans R Soc Lond B Biol Sci 355:1077-84, 2000. Pubmed reference: 11186309. DOI: 10.1098/rstb.2000.0645.
1998 Lamont, S.J. :
The chicken major histocompatibility complex and disease. Rev Sci Tech 17:128-42, 1998. Pubmed reference: 9638806.
1994 Kean, R.P., Briles, W.E., Cahaner, A., Freeman, A.E., Lamont, S.J. :
Differences in major histocompatibility complex frequencies after multitrait, divergent selection for immunocompetence. Poult Sci 73:7-17, 1994. Pubmed reference: 8165171.
1992 Plachy, J., Pink, J.R., Hála, K. :
Biology of the chicken MHC (B complex). Crit Rev Immunol 12:47-79, 1992. Pubmed reference: 1358107.
Yoo, B.H., Sheldon, B.L. :
Association of the major histocompatibility complex with avian leukosis virus infection in chickens. Br Poult Sci 33:613-20, 1992. Pubmed reference: 1322760. DOI: 10.1080/00071669208417500.
1987 Kim, C.D., Lamont, S.J., Rothschild, M.F. :
Genetic associations of body weight and immune response with the major histocompatibility complex in White Leghorn chicks. Poult Sci 66:1258-63, 1987. Pubmed reference: 2825154.
1986 Löliger, H.C., von dem Hagen, D., Krieg, R. :
[Effects of blood group markers (B allele), immunoglobulins and leukosis infections on the development of Marek's disease]. Dtsch Tierarztl Wochenschr 93:44-9, 1986. Pubmed reference: 3009129.
1984 Briles, W.E. :
Early chicken blood group investigations. Immunogenetics 20:217-26, 1984. Pubmed reference: 6088392.
1982 Briles, W.E., Briles, R.W. :
Identification of haplotypes of the chicken major histocompatibility complex (B). Immunogenetics 15:449-59, 1982. Pubmed reference: 7106863.
Briles, W.E., Bumstead, N., Ewert, D.L., Gilmour, D.G., Gogusev, J., Hála, K., Koch, C., Longenecker, B.M., Nordskog, A.W., Pink, J.R., Schierman, L.W., Simonsen, M., Toivanen, A., Toivanen, P., Vainio, O., Wick, G. :
Nomenclature for chicken major histocompatibility (B) complex. Immunogenetics 15:441-7, 1982. Pubmed reference: 7106862.
Longenecker, B.M. :
Major histocompatibility complex of chickens: genes, antigens, differential features, and special contributions to our knowledge of the advantages of polymorphism of cell surface antigens. Surv Immunol Res 1:205-11, 1982. Pubmed reference: 6821223.
1977 Stone, H.A., Briles, W.E., McGibbon, W.H. :
The influence of the major histocompatibility locus on Marek's disease in the chicken. Adv Exp Med Biol 88:299-307, 1977. Pubmed reference: 920518.
1975 Balcarová, J., Günther, E., Hála, K., Rüde, E., Hraba, T. :
Further evidence for the genetic control of immune responsiveness to (T,G)-A--L by the B system in chickens. Folia Biol (Praha) 21:406-8, 1975. Pubmed reference: 1239387.
Prevsner, I., Nordskog, A.W., Kaeberle, M.L. :
Immune response and the B blood group locus in chickens Genetics 80:753-759, 1975. Pubmed reference: 172405.
Yamamoto, Y. :
Relationship of B blood group locus to skin allograft in chickens. Anim Blood Groups Biochem Genet 6:19-24, 1975. Pubmed reference: 1106260.
Ziegler, A., Pink, J.R. :
Characterization of major histocompatibility (B) antigens of the chicken. Transplantation 20:523-7, 1975. Pubmed reference: 1209728.
1973 Gintovt, V.E., Novik, I.E., Kushner, K.h.F. :
[Genetic control of the B-system of blood groups in chickens]. Dokl Akad Nauk SSSR 210:215-7, 1973. Pubmed reference: 4122835.
Nordskog, A.W., Rishell, W.A., Briggs, D.M. :
Influence of B locus blood groups on adult mortality and egg production in the White Leghorn chicken. Genetics 75:181-9, 1973. Pubmed reference: 4762873.
1971 Hardin, R.T. :
Relationships between blood group alleles at the B-locus and economic traits in a population of non-inbred meat-type chickens. Poult Sci 50:1261-70, 1971. Pubmed reference: 5106712.
1970 Seet, C.P., Briles, C.O. :
The association of the A, B and E parental blood group system genotypes with fertility and hatchability in chickens. Poult Sci 49:922-6, 1970. Pubmed reference: 5485484.
1969 Schierman, L.W., McBride, R.A. :
Evidence for a mutational event at the B blood group-histocompatibility locus in chickens. Transplantation 8:515-6, 1969. Pubmed reference: 4192441.
1962 Allen, C.P., Gilmour, D.G. :
The B blood group system of chickens. III. The effects of two heterozygous genotypes on the survival and egg production of multiple crosses. Genetics 47:1711-8, 1962. Pubmed reference: 14012113.
1961 Briles, W.E., Allen, C.P. :
The B blood group system of chickens. II. The effects of genotype on livability and egg production in seven commercial inbred lines Genetics 46:1273-1293, 1961.
1959 Briles, C.O., McGibbon, W.H., Irwin, M.R. :
Additional Alleles Affecting Red Blood Cell Antigens in the Chicken. Genetics 44:955-65, 1959. Pubmed reference: 17247871.
1957 Briles, W.E., Allen, C.P., Millen, T.W. :
The B Blood Group System of Chickens. I. Heterozygosity in Closed Populations. Genetics 42:631-48, 1957. Pubmed reference: 17247723.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 14 Oct 2011