OMIA:000120-9031 : Blood group system B in Gallus gallus (chicken)

In other species: pig , aoudad , taurine cattle , goat , mouflon , sheep

Categories: Haematopoietic system phene

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal co-dominant

Considered a defect: no

Key variant known: no

Cross-species summary: Each blood group system consists of a set of blood types, each of which corresponds to a particular antigen (usually a glycoprotein) on the surface of red blood cells. The different types within a system are the result of the action of different alleles at a locus that usually encodes an enzyme that catalyses the creation of the feature of the glycoprotein unique to that type, e.g. the presence of a particular sugar at the end of a short chain of sugars.

Species-specific description: The B blood group system in chickens is also the major histocompatibility complex (MHC) of this species.

Inheritance: Briles et al. (1959) confirmed the existence of four loci (blood group systems), namely A, B, D, and E, with some evidence of tight linkage between A and E.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2011). OMIA:000120-9031: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2011 Chazara, O., Tixier-Boichard, M., Morin, V., Zoorob, R., Bed'hom, B. :
Organisation and diversity of the class II DM region of the chicken MHC. Mol Immunol 48:1263-71, 2011. Pubmed reference: 21481938. DOI: 10.1016/j.molimm.2011.03.009.
Walker, B.A., Hunt, L.G., Sowa, A.K., Skjødt, K., Göbel, T.W., Lehner, P.J., Kaufman, J. :
The dominantly expressed class I molecule of the chicken MHC is explained by coevolution with the polymorphic peptide transporter (TAP) genes. Proc Natl Acad Sci U S A 108:8396-401, 2011. Pubmed reference: 21536896. DOI: 10.1073/pnas.1019496108.
2006 Li, G.Q., Lu, L.Z., Wang, D.Q., Shen, J.D., Tao, Z.R., Zhao, A.Z., Yuan, A.P. :
[Advance in association studies of major histocompatibility complex (MHC) gene polymorphisms with traits of resistance against infectious disease in chickens]. Yi Chuan 28:893-8, 2006. Pubmed reference: 16825180.
2004 Miller, M.M., Bacon, L.D., Hala, K., Hunt, H.D., Ewald, S.J., Kaufman, J., Zoorob, R., Briles, W.E. :
2004 Nomenclature for the chicken major histocompatibility (B and Y) complex. Immunogenetics 56:261-79, 2004. Pubmed reference: 15257423. DOI: 10.1007/s00251-004-0682-1.
Taylor, R.L. :
Major histocompatibility (B) complex control of responses against Rous sarcomas. Poult Sci 83:638-49, 2004. Pubmed reference: 15109061.
2000 Kaufman, J. :
The simple chicken major histocompatibility complex: life and death in the face of pathogens and vaccines. Philos Trans R Soc Lond B Biol Sci 355:1077-84, 2000. Pubmed reference: 11186309. DOI: 10.1098/rstb.2000.0645.
1998 Lamont, S.J. :
The chicken major histocompatibility complex and disease. Rev Sci Tech 17:128-42, 1998. Pubmed reference: 9638806.
1994 Kean, R.P., Briles, W.E., Cahaner, A., Freeman, A.E., Lamont, S.J. :
Differences in major histocompatibility complex frequencies after multitrait, divergent selection for immunocompetence. Poult Sci 73:7-17, 1994. Pubmed reference: 8165171.
1992 Plachy, J., Pink, J.R., Hála, K. :
Biology of the chicken MHC (B complex). Crit Rev Immunol 12:47-79, 1992. Pubmed reference: 1358107.
Yoo, B.H., Sheldon, B.L. :
Association of the major histocompatibility complex with avian leukosis virus infection in chickens. Br Poult Sci 33:613-20, 1992. Pubmed reference: 1322760. DOI: 10.1080/00071669208417500.
1987 Kim, C.D., Lamont, S.J., Rothschild, M.F. :
Genetic associations of body weight and immune response with the major histocompatibility complex in White Leghorn chicks. Poult Sci 66:1258-63, 1987. Pubmed reference: 2825154.
1986 Löliger, H.C., von dem Hagen, D., Krieg, R. :
[Effects of blood group markers (B allele), immunoglobulins and leukosis infections on the development of Marek's disease]. Dtsch Tierarztl Wochenschr 93:44-9, 1986. Pubmed reference: 3009129.
1984 Briles, W.E. :
Early chicken blood group investigations. Immunogenetics 20:217-26, 1984. Pubmed reference: 6088392.
1982 Briles, W.E., Bumstead, N., Ewert, D.L., Gilmour, D.G., Gogusev, J., Hála, K., Koch, C., Longenecker, B.M., Nordskog, A.W., Pink, J.R., Schierman, L.W., Simonsen, M., Toivanen, A., Toivanen, P., Vainio, O., Wick, G. :
Nomenclature for chicken major histocompatibility (B) complex. Immunogenetics 15:441-7, 1982. Pubmed reference: 7106862.
Briles, W.E., Briles, R.W. :
Identification of haplotypes of the chicken major histocompatibility complex (B). Immunogenetics 15:449-59, 1982. Pubmed reference: 7106863.
Longenecker, B.M. :
Major histocompatibility complex of chickens: genes, antigens, differential features, and special contributions to our knowledge of the advantages of polymorphism of cell surface antigens. Surv Immunol Res 1:205-11, 1982. Pubmed reference: 6821223.
1977 Stone, H.A., Briles, W.E., McGibbon, W.H. :
The influence of the major histocompatibility locus on Marek's disease in the chicken. Adv Exp Med Biol 88:299-307, 1977. Pubmed reference: 920518.
1975 Balcarová, J., Günther, E., Hála, K., Rüde, E., Hraba, T. :
Further evidence for the genetic control of immune responsiveness to (T,G)-A--L by the B system in chickens. Folia Biol (Praha) 21:406-8, 1975. Pubmed reference: 1239387.
Prevsner, I., Nordskog, A.W., Kaeberle, M.L. :
Immune response and the B blood group locus in chickens Genetics 80:753-759, 1975. Pubmed reference: 172405.
Yamamoto, Y. :
Relationship of B blood group locus to skin allograft in chickens. Anim Blood Groups Biochem Genet 6:19-24, 1975. Pubmed reference: 1106260.
Ziegler, A., Pink, J.R. :
Characterization of major histocompatibility (B) antigens of the chicken. Transplantation 20:523-7, 1975. Pubmed reference: 1209728.
1973 Gintovt, V.E., Novik, I.E., Kushner, K.h.F. :
[Genetic control of the B-system of blood groups in chickens]. Dokl Akad Nauk SSSR 210:215-7, 1973. Pubmed reference: 4122835.
Nordskog, A.W., Rishell, W.A., Briggs, D.M. :
Influence of B locus blood groups on adult mortality and egg production in the White Leghorn chicken. Genetics 75:181-9, 1973. Pubmed reference: 4762873.
1971 Hardin, R.T. :
Relationships between blood group alleles at the B-locus and economic traits in a population of non-inbred meat-type chickens. Poult Sci 50:1261-70, 1971. Pubmed reference: 5106712.
1970 Seet, C.P., Briles, C.O. :
The association of the A, B and E parental blood group system genotypes with fertility and hatchability in chickens. Poult Sci 49:922-6, 1970. Pubmed reference: 5485484.
1969 Schierman, L.W., McBride, R.A. :
Evidence for a mutational event at the B blood group-histocompatibility locus in chickens. Transplantation 8:515-6, 1969. Pubmed reference: 4192441.
1962 Allen, C.P., Gilmour, D.G. :
The B blood group system of chickens. III. The effects of two heterozygous genotypes on the survival and egg production of multiple crosses. Genetics 47:1711-8, 1962. Pubmed reference: 14012113.
1961 Briles, W.E., Allen, C.P. :
The B blood group system of chickens. II. The effects of genotype on livability and egg production in seven commercial inbred lines Genetics 46:1273-1293, 1961.
1959 Briles, C.O., McGibbon, W.H., Irwin, M.R. :
Additional Alleles Affecting Red Blood Cell Antigens in the Chicken. Genetics 44:955-65, 1959. Pubmed reference: 17247871.
1957 Briles, W.E., Allen, C.P., Millen, T.W. :
The B Blood Group System of Chickens. I. Heterozygosity in Closed Populations. Genetics 42:631-48, 1957. Pubmed reference: 17247723.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 14 Oct 2011