OMIA:000147-9793 : Brachygnathia in Equus asinus

In other species: taurine cattle , sheep , horse , dog , alpaca , llama ,

Categories: Craniofacial phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Congenital abnormal shortness of the mandible (lower jaw), resulting in protrusion of the maxilla (upper jaw).

Markers: Using a comparative candidate gene strategy, based on evidence from humans, Rodrigues et al. (2013) could not identify any marker in the MATN1 gene (encoding Matrilin-1) to be associated with this disorder.

Breed: Zamorano-Leonés-Spain, Spain (Ass) (VBO_0001829).


2013 Rodrigues, J.B., Araújo, S., Guedes-Pinto, H., San Roman, F., Viegas, C., Bastos, E. :
Analysis of new Matrilin-1 gene variants in a case-control study related to dental malocclusions in Equus asinus. Gene 522:70-4, 2013. Pubmed reference: 23558247 . DOI: 10.1016/j.gene.2013.03.084.

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  • Created by Frank Nicholas on 29 Jan 2014