OMIA:000177-9615 : Cerebellar cortical atrophy in Canis lupus familiaris (dog) |
In other species: domestic cat , taurine cattle , sheep
Categories: Nervous system phene
Single-gene trait/disorder: yes
Mode of inheritance: Autosomal recessive
Disease-related: yes
Key variant known: no
Cross-species summary: Wasting (decrease) of the outer layer of the grey matter of the cerebellum (the part of the brain situated behind the two hemispheres and above the pons and medulla oblongata).
Inheritance: Olby et a. (2004) provided reasonable evidence supporting autosomal recessive inheritance in a family of American Staffordshire Terriers. A likely disease causing mutation has been identified in this breed - see 'lysosomal storage disease, ARSG related' (OMIA001503-9615) for further details.
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000177-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2023 | Stee, K., Van Poucke, M., Lowrie, M., Van Ham, L., Peelman, L., Olby, N., Bhatti, S.F.M. : |
Phenotypic and genetic aspects of hereditary ataxia in dogs. J Vet Intern Med 37:1306-1322, 2023. Pubmed reference: 37341581. DOI: 10.1111/jvim.16742. | |
2007 | Nibe, K., Kita, C., Morozumi, M., Awamura, Y., Tamura, S., Okuno, S., Kobayashi, T., Uchida, K. : |
Clinicopathological features of canine neuroaxonal dystrophy and cerebellar cortical abiotrophy in Papillon and Papillon-related dogs. J Vet Med Sci 69:1047-52, 2007. Pubmed reference: 17984592. DOI: 10.1292/jvms.69.1047. | |
2006 | Buijtels, J.J., Kroeze, E.J., Voorhout, G., Schellens, C.J., van Nes, J.J. : |
[Cerebellar cortical degeneration in an American Staffordshire terrier]. Tijdschr Diergeneeskd 131:518-22, 2006. Pubmed reference: 16916197. | |
2004 | Olby, N., Blot, S., Thibaud, JL., Phillips, J., O'Brien, DP., Burr, J., Berg, J., Brown, T., Breen, M. : |
Cerebellar cortical degeneration in adult American Staffordshire Terriers. J Vet Intern Med 18:201-8, 2004. Pubmed reference: 15058771. DOI: 10.1892/0891-6640(2004)18<201:ccdiaa>2.0.co;2. | |
2003 | Hanzlicek, D., Kathmann, I., Bley, T., Srenk, P., Botteron, C., Gaillard, C., Jaggy, A. : |
[Cerebellar cortical abiotrophy in American Staffordshire terriers: clinical and pathological description of 3 cases] Schweiz Arch Tierheilkd 145:369-75, 2003. Pubmed reference: 12951908. DOI: 10.1024/0036-7281.145.8.369. | |
2000 | van, Tongeren, S.E., van, Vonderen, I.K., van, Nes, J.J., van, den, Ingh, T.S.G.A.M. : |
Cerebellar cortical abiotrophy in two Portuguese Podenco littermates Veterinary Quarterly 22:172-174, 2000. Pubmed reference: 10952450. | |
1991 | Perille, A.L., Baer, K., Joseph, R.J., Carrillo, J.M., Averill, D.R. : |
Postnatal cerebellar cortical degeneration in Labrador Retriever puppies. Canadian Veterinary Journal - Revue Veterinaire Canadienne 32:619-621, 1991. |
Edit History
- Created by Frank Nicholas on 27 Oct 2005
- Changed by Imke Tammen2 on 08 Jan 2021
- Changed by Imke Tammen2 on 23 Jun 2023