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OMIA:000197-9615 : Cleft palate in Canis lupus familiaris

In other species: domestic cat , cattle , horse , pig , rabbit , American mink , chicken , sheep , spectacled flying fox

Categories: Digestive / alimentary phene , Craniofacial phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 106250 (trait) , 106260 (trait) , 114300 (trait) , 119300 (trait) , 119500 (trait) , 119530 (trait) , 119540 (trait) , 119550 (trait) , 119570 (trait) , 119580 (trait) , 120433 (trait) , 129400 (trait) , 129810 (trait) , 129830 (trait) , 129900 (trait) , 164220 (trait) , 179400 (trait) , 181180 (trait) , 201180 (trait) , 216100 (trait) , 216300 (trait) , 218090 (trait) , 225000 (trait) , 231060 (trait) , 241850 (trait) , 242840 (trait) , 244300 (trait) , 255995 (trait) , 258320 (trait) , 260150 (trait) , 261800 (trait) , 268300 (trait) , 277170 (trait) , 301815 (trait) , 303400 (trait) , 600331 (trait) , 600460 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Congenital fissure (split) that involves the hard or soft palate (roof of the mouth). Also known as palatoschisis.

Breeds: Brittany Spaniel, Labrador Retriever, Pyrenean Mountain Dog.

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2022 Goldschmidt, S., Hoyer, N. :
Management of dental and oral developmental conditions in dogs and cats. Vet Clin North Am Small Anim Pract 52:139-158, 2022. Pubmed reference: 34838248 . DOI: 10.1016/j.cvsm.2021.09.002.
2019 Roman, N., Carney, P.C., Fiani, N., Peralta, S. :
Incidence patterns of orofacial clefts in purebred dogs. PLoS One 14:e0224574, 2019. Pubmed reference: 31682628 . DOI: 10.1371/journal.pone.0224574.
2018 Conze, T., Ritz, I., Hospes, R., Wehrend, A. :
Management of cleft palate in puppies using a temporary prosthesis: A report of three cases. Vet Sci 5:, 2018. Pubmed reference: 29937523 . DOI: 10.3390/vetsci5030061.
2017 Moura, E., Pimpão, C.T. :
A numerical classification system for cleft lip and palate in the dog. J Small Anim Pract 58:610-614, 2017. Pubmed reference: 28887848 . DOI: 10.1111/jsap.12730.
Peralta, S., Fiani, N., Kan-Rohrer, K.H., Verstraete, F.J.M. :
Morphological evaluation of clefts of the lip, palate, or both in dogs. Am J Vet Res 78:926-933, 2017. Pubmed reference: 28738009 . DOI: 10.2460/ajvr.78.8.926.
2014 Davidson, A.P., Gregory, C., Dedrick, P. :
Successful management permitting delayed operative revision of cleft palate in a Labrador Retriever. Vet Clin North Am Small Anim Pract 44:325-329, 2014. Pubmed reference: 24580993 . DOI: 10.1016/j.cvsm.2013.11.002.
2009 Kemp, C., Thiele, H., Dankof, A., Schmidt, G., Lauster, C., Fernahl, G., Lauster, R. :
Cleft lip and/or palate with monogenic autosomal recessive transmission in Pyrenees shepherd dogs. Cleft Palate Craniofac J 46:81-8, 2009. Pubmed reference: 19115787 . DOI: 10.1597/06-229.1.
2001 Warzee, C.C., Bellah, J.R., Richards, D. :
Congenital unilateral cleft of the soft palate in six dogs. J Small Anim Pract 42:338-40, 2001. Pubmed reference: 11480899 .
1997 Elwood, J.M., Colquhoun, T.A. :
Observations on the prevention of cleft palate in dogs by folic acid and potential relevance to humans New Zealand Veterinary Journal 45:254-256, 1997.
1994 Richtsmeier, J.T., Sack, G.H., Grausz, H.M., Cork, L.C. :
Cleft palate with autosomal recessive transmission in Brittany spaniels Cleft Palate - Craniofacial Journal 31:364-371, 1994. Pubmed reference: 7986797 . DOI: 10.1597/1545-1569(1994)031<0364:CPWART>2.3.CO;2.
1973 Anon. :
Cleft palate : the elusive anomaly Gaines Dog Research Progress :?, 1973.
1971 Cooper, H.K., Mattern, G.W. :
Genetic studies of cleft lip and palate in dogs. Birth Defects Orig Artic Ser 7:98-100, 1971. Pubmed reference: 5173250 .
1967 Atherton, J.D. :
Cleft palate in the dog. Dent Pract Dent Rec 18:145-50, 1967. Pubmed reference: 5234825 .
1965 Anon. :
Cleft palate in dogs. Dent Stud 44:122, 1965. Pubmed reference: 5214700 .
Bleicher, N., Sloan, R.F., Gault, I.G., Ashley, F.L. :
Cleft palate in a dog. Cleft Palate J 45:56-61, 1965. Pubmed reference: 14232216 .
1961 Calnan, J. :
The comparative anatomy of cleft lip and palate. I. Classification of cleft lip and palate in dogs. Br J Plast Surg 14:180-4, 1961. Pubmed reference: 13875838 .

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 04 May 2023