OMIA:000247 : Cushing syndrome, ACTH-dependent, pituitary-dependent hyperadrenocorticism |
Categories: Endocrine / exocrine gland phene (incl mammary gland)
Possible human homologues (MIM numbers): 160980 (trait) , 219080 (trait) , 219090 (trait)
Cross-species summary: Entries for this type of Cushing syndrome (pituitary-dependent hyperadrenocorticism, pituitary pars intermedia dysfunction (PPID)) are included for some species under the phene 'Cushing syndrome, generic' (previously 'Hyperadrenocorticism, generic'): OMIA:000494. Renamed from 'Cushing disease, pituitary-dependent hyperadrenocorticism' to 'Cushing syndrome, ACTH-dependent, pituitary-dependent hyperadrenocorticism based on ALIVE recommendations (PMID:40872711), with the following definiton: "Hypercortisolism occurs due to dysregulated ACTH secretion by the pituitary. This is generally associated with pituitary neoplasia or hyperplasia"
Species in which this phene is found:
dog (Canis lupus familiaris)
domestic cat (Felis catus)
Grevy's zebra (Equus grevyi)
Przewalski's horse (Equus przewalskii)
plains zebra (Equus quagga)
Edit History
- Created by Frank Nicholas on 03 May 2005
- Changed by Imke Tammen2 on 04 Nov 2020
- Changed by Imke Tammen2 on 20 Mar 2022
- Changed by Imke Tammen2 on 08 Feb 2024
- Changed by Imke Tammen2 on 07 Jun 2024
- Changed by Imke Tammen2 on 10 Sep 2025