OMIA:000249-9823 : Cyclopia in Sus scrofa (pig)

In other species: chicken , dog , domestic cat , horse , taurine cattle , sheep , rabbit , American mink

Categories: Vision / eye phene , Craniofacial phene

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: A congenital developmental disorder characterised by a single orbital fossa (eye socket). Named after the race of one-eyed giants of Greek mythology. In humans, this disorder is often associated with a chromosomal abnormality.

Species-specific description: In a reported case in pigs (Arakaki and Vogt, 1976), the affected animal, which died within an hour of birth, was shown to have a normal karyotype.

Inheritance: There is no evidence on the inheritance of this disorder in pigs.

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2011). OMIA:000249-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1991 Baljet, B., van der Werf, F., Otto, A.J. :
Willem Vrolik on cyclopia. Doc Ophthalmol 77:355-68, 1991. Pubmed reference: 1769305.
1987 Evans, H.E. :
Cyclopia, situs inversus and widely patent ductus arteriosus in a new-born pig, Sus scrofa. Anat Histol Embryol 16:221-6, 1987. Pubmed reference: 3125763.
1982 Ollivier, L., Sellier, P. :
Pig genetics: a review Annales de Genetique et de Selection Animale 14:481-544, 1982.
1976 Arakaki, D.T., Vogt, D.W. :
A porcine cyclops with normal female karyotype American Journal of Veterinary Research 37:95-96, 1976. Pubmed reference: 1247205.
1973 Köhler, H. :
[Porcine cyclops]. Dtsch Tierarztl Wochenschr 80:130, 1973. Pubmed reference: 4200005.
1972 Carmona de Uzcategui, M.L., Kleiss, E. :
[Cyclopia. A preliminary note about an observation in the pig, Sus scrofa L]. Zentralbl Veterinarmed C 1:21-6, 1972. Pubmed reference: 4626077.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 17 Oct 2011