OMIA:000249-9940 : Cyclopia in Ovis aries (sheep)

In other species: chicken , dog , domestic cat , horse , pig , taurine cattle , rabbit , American mink

Categories: Craniofacial phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: A congenital developmental disorder characterised by a single orbital fossa (eye socket). Named after the race of one-eyed giants of Greek mythology. In humans, this disorder is often associated with a chromosomal abnormality.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2011). OMIA:000249-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset].


1991 Baljet, B., van der Werf, F., Otto, A.J. :
Willem Vrolik on cyclopia. Doc Ophthalmol 77:355-68, 1991. Pubmed reference: 1769305.

Edit History

  • Created by Frank Nicholas on 17 Oct 2011