OMIA:000267-9986 : Delta 9-tetrahydrocannabinol seizure in Oryctolagus cuniculus (rabbit)

Categories: Nervous system phene

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal recessive

Considered a defect: yes

Key variant known: no

Species-specific symbol: thc

Species-specific description: Fish et al. (1981): "Delta 9-Tetrahydrocannabinol (THC), the major psychoactive ingredient of marijuana, causes nonfatal convulsions in rabbits of a closed colony of New Zealand White rabbits (Uaz: NZW). The convulsive phenotype appears to be associated with homozygous expression of a single autosomal recessive gene with full penetrance."

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:000267-9986: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1983 Fish, B.S., Consroe, P. :
The ontogeny of delta-9-tetrahydrocannabinol responsiveness in the rabbit. Dev Psychobiol 16:147-58, 1983. Pubmed reference: 6299864. DOI: 10.1002/dev.420160207.
Fish, B.S., Consroe, P., Fox, R.R. :
Convulsant-anticonvulsant properties of delta-9-tetrahydrocannabinol in rabbits. Behav Genet 13:205-11, 1983. Pubmed reference: 6305325.
1981 Fish, B.S., Consroe, P., Fox, R.R. :
Inheritance of delta 9-tetrahydrocannabinol seizure susceptibility in rabbits. J Hered 72:215-6, 1981. Pubmed reference: 6268703.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 15 Sep 2011
  • Changed by Imke Tammen2 on 13 Oct 2022