OMIA:000277-9615 : Diabetes in Canis lupus familiaris (dog)

In other species: chimpanzee , domestic cat , domestic guinea pig , long-tailed chinchilla

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:000277-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Schermerhorn, T. :
Treating inflammatory conditions such as periodontal disease can improve glycaemic control in diabetic dogs. Vet Rec 194:34-35, 2024. Pubmed reference: 38180220. DOI: 10.1002/vetr.3822.
2021 O'Kell, A.L., Wasserfall, C., Guingab-Cagmat, J., Webb-Roberston, B.M., Atkinson, M.A., Garrett, T.J. :
Targeted metabolomic analysis identifies increased serum levels of GABA and branched chain amino acids in canine diabetes. Metabolomics 17:100, 2021. Pubmed reference: 34775536. DOI: 10.1007/s11306-021-01850-y.
2016 Foale, R., Referrals, D.W. :
Trial of gene therapy in diabetic dogs. Vet Rec 179:550, 2016. Pubmed reference: 27885133. DOI: 10.1136/vr.i6278.
Kang, M.H., Kim, D.H., Jeong, I.S., Choi, G.C., Park, H.M. :
Evaluation of four portable blood glucose meters in diabetic and non-diabetic dogs and cats. Vet Q 36:2-9, 2016. Pubmed reference: 26442786. DOI: 10.1080/01652176.2015.1092617.
2002 Connally, H.E. :
Critical care monitoring considerations for the diabetic patient Clinical Techniques in Small Animal Practice 17:73-78, 2002. Pubmed reference: 12219720. DOI: 10.1053/svms.2002.33039.
Davison, L., Catchpole, B., Herrtage, M., Church, D. :
Research into canine diabetes mellitus Veterinary Record 150:356, 2002.
Mathes, M.A. :
Home monitoring of the diabetic pet Clinical Techniques in Small Animal Practice 17:86-95, 2002. Pubmed reference: 12219722. DOI: 10.1053/svms.2002.33040.
Neuvians, T.P., Berger, M. :
Diabetes care in cats and dogs Diabetic Medicine 19:77-79, 2002. Pubmed reference: 11869308.
Tune, J.D., Yeh, C., Setty, S., Zong, P., Downey, H.F. :
Coronary blood flow control is impaired at rest and during exercise in conscious diabetic dogs Basic Research in Cardiology 97:248-257, 2002. Pubmed reference: 12061395.
2000 Anon. :
Operating on a dog with diagnosed diabetes [Dutch] Tijdschrift voor Diergeneeskunde 125:524-525, 2000. Pubmed reference: 11002501.
Arai, T., Takahashi, S., Takahashi, M., Tanaka, A., Sasaki, N., Sako, T. :
Gene expression of glycolytic enzymes in blood cell of diabetic dogs Revue de Medecine Veterinaire 151:658, 2000.
Rashid, S., Shi, Z.Q., Niwa, M., Mathoo, J.M.R., Vandelangeryt, M., Bilinski, D., Lewis, G.F., Vranic, M. :
beta-blockade, but not normoglycemia or hyperinsulinemia, markedly diminishes stress-induced hyperglycemia in diabetic dogs Diabetes 49:253-262, 2000. Pubmed reference: 10868942.
Salgado, D., Reusch, C., Spiess, B. :
Diabetic cataracts: Different incidence between dogs and cats Schweizer Archiv fur Tierheilkunde 142:349-353, 2000. Pubmed reference: 10892302.
1999 Ghani, M., Malik, R.A., Walker, D., Sharma, A.K., Lowrie, C.T., Schall, W.D., Boulton, A.J.M. :
Perineurial abnormalities in the spontaneously diabetic dog Acta Neuropathologica 97:98-102, 1999. Pubmed reference: 9930901.
Kern, T.S., Engerman, R.L. :
Aldose reductase and the development of renal disease in diabetic dogs Journal of Diabetes & its Complications 13:10-16, 1999.
1998 Oshea, T. :
Coping with the diabetic dog Irish Veterinary Journal 51:382, 1998.
1997 Braun, J.P., Medaille, C. :
Diagnosis and monitoring of diabetes mellitus in dogs and cats - use of fructosamine measurement - a review [Review] [French] Revue de Medecine Veterinaire 148:945-950, 1997.
Fisher, S.J., Lekas, M., Shi, Z.Q., Bilinski, D., Carvalho, G., Giacca, A., Vranic, M. :
Insulin-independent acute restoration of euglycemia normalizes the impaired glucose clearance during exercise in diabetic dogs Diabetes 46:1805-1812, 1997. Pubmed reference: 9356030.
Freyse, E.J., Rebrin, K., Schneider, T., Petrzika, M., Fischer, U. :
Nitrogen economy in insulin dependent, normoglycemic diabetic dogs Zeitschrift fur Ernahrungswissenschaft 36:355, 1997.
Freyse, E.J., Becher, T., Elhag, O., Knospe, S., Goke, B., Fischer, U. :
Blood glucose lowering and glucagonostatic effects of glucagon-like peptide i in insulin-deprived diabetic dogs Diabetes 46:824-828, 1997. Pubmed reference: 9133550.
Graham, P.A., Nash, A.S., Mckellar, Q.A. :
Pharmacokinetics of a porcine insulin zinc suspension in diabetic dogs Journal of Small Animal Practice 38:434-438, 1997. Pubmed reference: 9358402.
Kwong, L.K., Yeager, C., Allen, K., Le, H., Gleeson, J.M., Ridinger, D.N., Wilson, D.E. :
Plasma lipoprotein response to dietary fat in diabetic dogs Journal of Experimental Animal Science 38:134-146, 1997.
Myers, S.R., Yakubumadus, F.E., Johnson, W.T., Baker, J.E., Cusick, T.S., Williams, V.K., Tinsley, F.C., Kriauciunas, A., Manetta, J., Chen, V.J. :
Acylation of human insulin with palmitic acid extends the time action of human insulin in diabetic dogs Diabetes 46:637-642, 1997. Pubmed reference: 9075804.
1996 Fisher, S.J., Lekas, M.C., Mccall, R.H., Shi, Z.Q., Giacca, A., Vranic, M. :
Determinants of glucose turnover in the pathophysiology of diabetes - an in vivo analysis in diabetic dogs Diabete et Metabolisme 22:111-121, 1996.
Freyse, E.J., Rebrin, K., Schneider, T., Petrzika, M., Fischer, U. :
Increased urea synthesis in insulin-dependent diabetic dogs maintained normoglycemic - effect of portal insulin administration and food protein content Diabetes 45:667-674, 1996. Pubmed reference: 8621020.
Nagaraj, R.H., Kern, T.S., Sell, D.R., Fogarty, J., Engerman, R.L., Monnier, V.M. :
Evidence of a glycemic threshold for the formation of pentosidine in diabetic dog lens but not in collagen Diabetes 45:587-594, 1996. Pubmed reference: 8621008.
1994 Engerman, R.L., Kern, T.S., Larson, M.E. :
Nerve Conduction and Aldose Reductase Inhibition During 5 Years of Diabetes or Galactosaemia in Dogs Diabetologia 37:141-144, 1994. Pubmed reference: 8163047.
Gardiner, T.A., Stitt, A.W., Anderson, H.R., Archer, D.B. :
Selective Loss of Vascular Smooth Muscle Cells in the Retinal Microcirculation of Diabetic Dogs British Journal of Ophthalmology 78:54-60, 1994. Pubmed reference: 8110701.
Lancaster, R.L., Haut, R.C., Decamp, C.E. :
Changes in the mechanical properties of patellar tendon preparations of spontaneously diabetic dogs under long-term insulin therapy Journal of Biomechanics 27:1105-1108, 1994. Pubmed reference: 8089166.
Miles, P.D.G., Yamatani, K., Brown, M.R., Lickley, H.L.A., Vranic, M. :
Intracerebroventricular administration of somatostatin octapeptide counteracts the hormonal and metabolic responses to stress in normal and diabetic dogs Metabolism - Clinical and Experimental 43:1134-1143, 1994. Pubmed reference: 7916119.
Nomura, M., Kubota, M.A., Kawamori, R., Yamasaki, Y., Kamada, T., Abe, H. :
Effect of addition of hyaluronic acid to highly concentrated insulin on absorption from the conjunctiva in conscious diabetic dogs Journal of Pharmacy and Pharmacology 46:768-770, 1994. Pubmed reference: 7837049.
1993 Reusch, C.E., Liehs, M.R., Hoyer, M., Vochezer, R. :
Fructosamine - A New Parameter for Diagnosis and Metabolic Control in Diabetic Dogs and Cats Journal of Veterinary Internal Medicine 7:177-182, 1993. Pubmed reference: 8331612.
Salzsieder, E., Albrecht, G., Fischer, U., Stowhas, H., Fritze, K., Stephen, R.L., Carson, E.R. :
Estimation of Individual Action Profiles of Therapeutically Administered Insulin Based on Blood Glucose Levels in Diabetic Dogs and Patients Diabetes Nutrition & Metabolism 6:261-275, 1993.
Sieber, F.E., Brown, P.R., Wu, Y., Koehler, R.C., Traystman, R.J. :
Cerebral Blood Flow and Metabolism in Dogs with Chronic Diabetes Anesthesiology 79:1013-1021, 1993. Pubmed reference: 8238980.
1989 Kern, T.S., Engerman, R.L. :
Comparison of DNA Breaks in Diabetic Dogs and Galactosemic Dogs Developing Retinopathy Current Eye Research 8:765-769, 1989. Pubmed reference: 2791624.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 30 Jan 2022