OMIA 000326-8839 : Egg shell colour in Anas platyrhynchos

In other species: chicken

Mendelian trait/disorder: unknown

Considered a defect: no

Mapping: Liu et al. (2021) used genome-wide association analysis and identity by descent to finely map green egg colour to a 179-kb region of Chr4 based on the resequencing of 352 ducks (Anas platyrhynchos) from a segregating population resulting from the mating of Pekin ducks (white-shelled eggs) and mallards (green-shelled eggs). We further narrowed the candidate region to a 30-kb interval ... . Among the genes located in the finely mapped region, only one transcript of the ABCG2 gene (XM_013093252.2) exhibited higher uterine expression in green-shelled individuals than in white-shelled individuals, as supported by transcriptome data from four populations. ABCG2 has been reported to encode a protein that functions as a membrane transporter for biliverdin. Sanger sequencing of the whole 30-kb candidate region (Chr4: 47.41-47.44 Mb) and a plasmid reporter assay helped to identify a single nucleotide polymorphism (Chr4: 47,418,074 G>A) located in a conserved predicted promoter region whose variation may alter ABCG2 transcription activity."


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Liu, H., Hu, J., Guo, Z., Fan, W., Xu, Y., Liang, S., Liu, D., Zhang, Y., Xie, M., Tang, J., Huang, W., Zhang, Q., Xi, Y., Li, Y., Wang, L., Ma, S., Jiang, Y., Feng, Y., Wu, Y., Cao, J., Zhou, Z., Hou, S. :
A single nucleotide polymorphism variant located in the cis-regulatory region of the ABCG2 gene is associated with mallard egg colour. Mol Ecol 30:1477-91, 2021. Pubmed reference: 33372351. DOI: 10.1111/mec.15785.
2019 Bai, D.P., Lin, X.Y., Wu, Y., Zhou, S.Y., Huang, Z.B., Huang, Y.F., Li, A., Huang, X.H. :
Isolation of blue-green eggshell pigmentation-related genes from Putian duck through RNA-seq. BMC Genomics 20:66, 2019. Pubmed reference: 30660177. DOI: 10.1186/s12864-019-5436-4.

Edit History

  • Created by Imke Tammen2 on 17 Aug 2021
  • Changed by Imke Tammen2 on 17 Aug 2021
  • Changed by Imke Tammen2 on 25 Aug 2021