OMIA:000413-9685 : Glomerulonephritis in Felis catus (domestic cat)

In other species: dog

Categories: Renal / urinary system phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 137940 (trait) , 247800 (trait) , 248760 (trait) , 305800 (trait)

Mendelian trait/disorder: unknown

Considered a defect: yes

Clinical features: Presents as nephrotic syndrome: progressive proteinuria, hypoproteinaemia (hypoalbuminaemia), hypercholesteraemia, edema, and/or effusion (White et al., 2008). Progressive clinical signs include weight loss, weakness, depression, anorexia, polydipsia, polyuria, nocturia as well as dehydration, subcutaneous edema, nonregenerative anemia, metabolic acidosis, oral and gastric ulcerations, and secondary renal hyperparathyroidism (Krakowka, 1978). (Compiled by Rachel Natsume 13/9/2021)

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:000413-9685: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2019 Rossi, F., Aresu, L., Martini, V., Trez, D., Zanetti, R., Coppola, L.M., Ferri, F., Zini, E. :
Immune-complex glomerulonephritis in cats: a retrospective study based on clinico-pathological data, histopathology and ultrastructural features. BMC Vet Res 15:303, 2019. Pubmed reference: 31429743. DOI: 10.1186/s12917-019-2046-y.
2011 Kamiie, J., Haishima, A., Inoue, K., Ogihara, K., Ono, M., Yasuno, K., Kobayashi, R., Aihara, N., Ohmuro, T., Shirota, K. :
Progression of glomerulonephritis to end-stage kidney disease in a cat with nephrotic syndrome. J Vet Med Sci 73:129-32, 2011. Pubmed reference: 20823662.
2008 White, J.D., Norris, J.M., Bosward, K.L., Fleay, R., Lauer, C., Malik, R. :
Persistent haematuria and proteinuria due to glomerular disease in related Abyssinian cats. J Feline Med Surg 10:219-29, 2008. Pubmed reference: 18455462. DOI: 10.1016/j.jfms.2007.11.007.
2001 Grant, D.C., Forrester, S.D. :
Glomerulonephritis in dogs and cats: Glomerular function, pathophysiology and clinical signs Compendium on Continuing Education for the Practicing Veterinarian 23:739-+, 2001.
Grant, D.C., Forrester, S.D. :
Glomerulonephritis in dogs and cats: Diagnosis and treatment Compendium on Continuing Education for the Practicing Veterinarian 23:798-805, 2001.
1984 August, J.R., Leib, M.S. :
Primary renal diseases of the cat. Vet Clin North Am Small Anim Pract 14:1247-60, 1984. Pubmed reference: 6393554. DOI: 10.1016/s0195-5616(84)50156-9.
1982 Hayashi, T., Ishida, T., Fujiwara, K. :
Glomerulonephritis associated with feline infectious peritonitis. Nihon Juigaku Zasshi 44:909-16, 1982. Pubmed reference: 7182631. DOI: 10.1292/jvms1939.44.909.
1979 Slauson, D.O., Lewis, R.M. :
Comparative pathology of glomerulonephritis in animals. Vet Pathol 16:135-64, 1979. Pubmed reference: 442447. DOI: 10.1177/030098587901600201.
1978 Glick, A.D., Horn, R.G., Holscher, M. :
Characterization of feline glomerulonephritis associated with viral-induced hematopoietic neoplasms. Am J Pathol 92:321-32, 1978. Pubmed reference: 677265.
Krakowka, S. :
Glomerulonephritis in dogs and cats. Vet Clin North Am 8:629-39, 1978. Pubmed reference: 155922. DOI: 10.1016/s0091-0279(78)50104-4.
1973 Churg, J., Ehrenreich, T. :
Membranous nephropathy. Perspect Nephrol Hypertens 1 Pt 1:443-8, 1973. Pubmed reference: 4536436.
1971 Farrow, B.R., Huxtable, C.R. :
Membranous nephropathy and the nephrotic syndrome in the cat. J Comp Pathol 81:463-7, 1971. Pubmed reference: 5167495.
1969 Farrow, B.R., Huxtable, C.R., McGovern, V.J. :
Nephrotic syndrome in the cat due to diffuse membranous glomerulonephritis. Pathology 1:67-72, 1969. Pubmed reference: 5408671.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 13 Sep 2021