OMIA:000552-9612 : Immunoglobulin A deficiency in Canis lupus (gray wolf)
In other species: dog
Categories: Immune system phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Species-specific description: By estimating the concentration of IgA in the serum of 71 gray wolves, Frankowiack et al. (2013) concluded that "the vast majority of wolves, the ancestor of the dog, are IgA deficient".
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
|2013||Frankowiack, M., Hellman, L., Zhao, Y., Arnemo, J.M., Lin, M., Tengvall, K., Møller, T., Lindblad-Toh, K., Hammarström, L. :|
|IgA deficiency in wolves. Dev Comp Immunol 40:180-4, 2013. Pubmed reference: 23352622. DOI: 10.1016/j.dci.2013.01.005.|
- Created by Frank Nicholas on 06 Feb 2013
- Changed by Frank Nicholas on 05 Aug 2013