OMIA:000552-9612 : Immunoglobulin A deficiency in Canis lupus (gray wolf)

In other species: dog

Categories: Immune system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific description: By estimating the concentration of IgA in the serum of 71 gray wolves, Frankowiack et al. (2013) concluded that "the vast majority of wolves, the ancestor of the dog, are IgA deficient".

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2013). OMIA:000552-9612: Online Mendelian Inheritance in Animals (OMIA) [dataset].


2013 Frankowiack, M., Hellman, L., Zhao, Y., Arnemo, J.M., Lin, M., Tengvall, K., Møller, T., Lindblad-Toh, K., Hammarström, L. :
IgA deficiency in wolves. Dev Comp Immunol 40:180-4, 2013. Pubmed reference: 23352622. DOI: 10.1016/j.dci.2013.01.005.

Edit History

  • Created by Frank Nicholas on 06 Feb 2013
  • Changed by Frank Nicholas on 05 Aug 2013