OMIA 000662-9823 : Motor neuron disease, lower in Sus scrofa

In other species: dog , horse , sheep

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific description: In presenting extensive pathological information on this disorder, O'Toole et al. (1994) concluded that a likely cause was primary or secondary mitochondrial dysfunction, possibly due to mutation(s) in mitochondrial DNA.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
1994 O'Toole, D., Ingram, J., Welch, V., Bardsley, K., Haven, T., Nunamaker, C., Wells, G. :
An Inherited Lower Motor Neuron Disease of Pigs - Clinical Signs in 2 Litters and Pathology of an Affected Pig Journal of Veterinary Diagnostic Investigation 6:62-71, 1994. Pubmed reference: 8011784.
O'Toole, D., Wells, G., Ingram, J., Cooley, W., Hawkins, S. :
Ultrastructural Pathology of an Inherited Lower Motor Neuron Disease of Pigs Journal of Veterinary Diagnostic Investigation 6:230-237, 1994. Pubmed reference: 8068756.
1993 O'Toole, D., Welch, V., Redland, K. :
Ubiquitin Immunocytochemistry of Spinal Cord in an Inherited Porcine Motor Neuron Disease Journal of Veterinary Diagnostic Investigation 5:642-646, 1993. Pubmed reference: 8286475.
1987 Wells, G.A.H., O'Toole, D.T., Wijeratne, W.V.L. :
An inherited neuronal system degeneration of the pig Neuropathology and Applied Neurobiology 13:233 only (abstract), 1987.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005