OMIA:000662-9823 : Motor neuron disease, lower in Sus scrofa (pig)
Categories: Nervous system phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Species-specific description: In presenting extensive pathological information on this disorder, O'Toole et al. (1994) concluded that a likely cause was primary or secondary mitochondrial dysfunction, possibly due to mutation(s) in mitochondrial DNA.
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|1994||O'Toole, D., Ingram, J., Welch, V., Bardsley, K., Haven, T., Nunamaker, C., Wells, G. :|
|An Inherited Lower Motor Neuron Disease of Pigs - Clinical Signs in 2 Litters and Pathology of an Affected Pig Journal of Veterinary Diagnostic Investigation 6:62-71, 1994. Pubmed reference: 8011784.|
|O'Toole, D., Wells, G., Ingram, J., Cooley, W., Hawkins, S. :|
|Ultrastructural Pathology of an Inherited Lower Motor Neuron Disease of Pigs Journal of Veterinary Diagnostic Investigation 6:230-237, 1994. Pubmed reference: 8068756.|
|1993||O'Toole, D., Welch, V., Redland, K. :|
|Ubiquitin Immunocytochemistry of Spinal Cord in an Inherited Porcine Motor Neuron Disease Journal of Veterinary Diagnostic Investigation 5:642-646, 1993. Pubmed reference: 8286475.|
|1987||Wells, G.A.H., O'Toole, D.T., Wijeratne, W.V.L. :|
|An inherited neuronal system degeneration of the pig Neuropathology and Applied Neurobiology 13:233 only (abstract), 1987.|
- Created by Frank Nicholas on 06 Sep 2005