OMIA 000715-9615 : Neuroaxonal dystrophy, generic in Canis lupus familiaris

In other species: domestic cat , sheep , horse , rabbit

Possibly relevant human trait(s) and/or gene(s) (MIM number): 608507 (gene)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Progressive ataxia, hypermetria, proprioceptive deficits, head incoordination and tremors.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2016 Pintus, D., Cancedda, M.G., Macciocu, S., Contu, C., Ligios, C. :
Pathological findings in a Dachshund-cross dog with neuroaxonal dystrophy. Acta Vet Scand 58:37, 2016. Pubmed reference: 27267214. DOI: 10.1186/s13028-016-0218-3.
2010 Nibe, K., Nakayama, H., Uchida, K. :
Comparative Study of Cerebellar Degeneration in Canine Neuroaxonal Dystrophy, Cerebellar Cortical Abiotrophy, and Neuronal Ceroid-Lipofuscinosis. J Vet Med Sci :, 2010. Pubmed reference: 20585192.
1997 Bennnett, P.F., Clarke, R.E. :
Laryngeal paralysis in a rottweiler with neuroaxonal dystrophy Australian Veterinary Journal 75:784-786, 1997. Pubmed reference: 9404606.
1993 Sacre, B.J., Cummings, J.F., Delahunta, A. :
Neuroaxonal Dystrophy in a Jack Russell Terrier Pup Resembling Human Infantile Neuroaxonal Dystrophy Cornell Veterinarian 83:133-142, 1993. Pubmed reference: 8467699.
1982 Clark, R.G., Hartley, W.J., Burgess, G.S., Cameron, J.S., Mitchell, G. :
Suspected inherited cerebellar neuroaxonal dystrophy in collie sheep dogs. N Z Vet J 30:102-3, 1982. Pubmed reference: 16030883. DOI: 10.1080/00480169.1982.34897.

Edit History

  • Created by Frank Nicholas on 10 Jun 2011
  • Changed by Martha MaloneyHuss on 17 Aug 2011
  • Changed by Frank Nicholas on 03 Sep 2011
  • Changed by Vicki Meyers-Wallen on 18 Sep 2011
  • Changed by Frank Nicholas on 12 Dec 2011
  • Changed by Tosso Leeb on 29 May 2013
  • Changed by Frank Nicholas on 29 Jun 2018