OMIA:000715-9615 : Neuroaxonal dystrophy, generic in Canis lupus familiaris (dog)

In other species: domestic cat , horse , sheep , rabbit

Categories: Nervous system phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 608507 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Progressive ataxia, hypermetria, proprioceptive deficits, head incoordination and tremors.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2018). OMIA:000715-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2016 Pintus, D., Cancedda, M.G., Macciocu, S., Contu, C., Ligios, C. :
Pathological findings in a Dachshund-cross dog with neuroaxonal dystrophy. Acta Vet Scand 58:37, 2016. Pubmed reference: 27267214. DOI: 10.1186/s13028-016-0218-3.
2010 Nibe, K., Nakayama, H., Uchida, K. :
Comparative study of cerebellar degeneration in canine neuroaxonal dystrophy, cerebellar cortical abiotrophy, and neuronal ceroid-lipofuscinosis. J Vet Med Sci 72:1495-9, 2010. Pubmed reference: 20585192. DOI: 10.1292/jvms.10-0072.
1997 Bennnett, P.F., Clarke, R.E. :
Laryngeal paralysis in a rottweiler with neuroaxonal dystrophy Australian Veterinary Journal 75:784-786, 1997. Pubmed reference: 9404606.
1993 Sacre, B.J., Cummings, J.F., Delahunta, A. :
Neuroaxonal Dystrophy in a Jack Russell Terrier Pup Resembling Human Infantile Neuroaxonal Dystrophy Cornell Veterinarian 83:133-142, 1993. Pubmed reference: 8467699.
1982 Clark, R.G., Hartley, W.J., Burgess, G.S., Cameron, J.S., Mitchell, G. :
Suspected inherited cerebellar neuroaxonal dystrophy in collie sheep dogs. N Z Vet J 30:102-3, 1982. Pubmed reference: 16030883. DOI: 10.1080/00480169.1982.34897.

Edit History

  • Created by Frank Nicholas on 10 Jun 2011
  • Changed by Martha MaloneyHuss on 17 Aug 2011
  • Changed by Frank Nicholas on 03 Sep 2011
  • Changed by Vicki Meyers-Wallen on 18 Sep 2011
  • Changed by Frank Nicholas on 12 Dec 2011
  • Changed by Tosso Leeb on 29 May 2013
  • Changed by Frank Nicholas on 29 Jun 2018