OMIA 000751-9615 : Osteochondritis dissecans in Canis lupus familiaris

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 181440 (trait) , 188700 (trait) , 259200 (trait)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: A joint disorder caused by blood deprivation in the subchondral bone causing the subchondral bone to die in a process called avascular necrosis. The bone is then reabsorbed by the body, leaving the articular cartilage it supported prone to damage. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these osteochondral fragments within the joint space, causing pain and further damage [HPO: 0010886]. Also called 'Osteochondrosis dissecans'

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2016 Ohlerth, S., Senn, S., Geissb├╝hler, U., Kircher, P., Fl├╝ckiger, M. :
Prevalence of humeral head osteochondrosis in the Greater Swiss Mountain dog and the Border Collie in Switzerland. Schweiz Arch Tierheilkd 158:749-754, 2016. Pubmed reference: 27821378. DOI: 10.17236/sat00091.
2011 Brunnberg, M.M., Engelke, E., Gielen, I.M., van Bree, H.J., Hoffmann, J.E., Brunnberg, L., Waibl, H.R. :
Cartilage thickness of the trochlea of the talus, with emphasis on sites predisposed to osteochondrosis dissecans, in clinically normal juvenile and adult dogs. Am J Vet Res 72:1318-24, 2011. Pubmed reference: 21962273. DOI: 10.2460/ajvr.72.10.1318.
2010 Hartmann, P., Stock, KF., Distl, O. :
[Multivariate genetic analysis of canine hip and elbow dysplasia as well as humeral osteochondrosis in the Bernese mountain dog]. Berl Munch Tierarztl Wochenschr 123:488-95, 2010. Pubmed reference: 21141279.
2006 Samoy, Y., Van Ryssen, B., Gielen, I., Walschot, N., Van Bree, H. :
Review of the literature: elbow incongruity in the dog. Vet Comp Orthop Traumatol 19:1-8, 2006. Pubmed reference: 16594537.
2000 Lehmann, K., Nell, B., Hittmair, K. :
The use of arthroscopy in a dog with osteochondrosis dissecans of the medial trochlear ridge of the talus [German] Wiener Tierarztliche Monatsschrift 87:322-327, 2000.
1998 Johnston, S.A. :
Osteochondritis dissecans of the humeral head Veterinary Clinics of North America - Small Animal Practice 28:33 ff., 1998.
1993 Fox, S.M., Walker, A.M. :
The Diagnostic Procedures and Therapy for OCD of the Hindlimbs Veterinary Medicine 88:147-153, 1993.
Fox, S.M., Walker, A.M. :
OCD of the Humeral Head - Its Diagnosis and Treatment Veterinary Medicine 88:123, 1993.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 05 Oct 2011