OMIA:000753-9615 : Osteodystrophy in Canis lupus familiaris (dog)

In other species: domestic cat , taurine cattle , rabbit

Categories: Skeleton phene (incl. short stature & teeth)

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 103580 (trait) , 600430 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:000753-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Perry, K.M., Enders, B.D., Negrão Watanabe, T.T. :
Refractory shock, hypercoagulability, and multiorgan thrombosis associated with hypertrophic osteodystrophy in a dog. J Vet Emerg Crit Care (San Antonio) , 2023. Pubmed reference: 36799891. DOI: 10.1111/vec.13280.
2021 Selman, J., Towle Millard, H. :
Hypertrophic osteodystrophy in dogs: diagnosis and treatment. J Small Anim Pract , 2021. Pubmed reference: 34490906. DOI: 10.1111/jsap.13413.
2016 Safra, N., Hitchens, P.L., Maverakis, E., Mitra, A., Korff, C., Johnson, E., Kol, A., Bannasch, M.J., Pedersen, N.C., Bannasch, D.L. :
Serum levels of innate immunity cytokines are elevated in dogs with metaphyseal osteopathy (hypertrophic osteodytrophy) during active disease and remission. Vet Immunol Immunopathol 179:32-5, 2016. Pubmed reference: 27590423. DOI: 10.1016/j.vetimm.2016.08.003.
2006 Crumlish, PT., Sweeney, T., Jones, B., Angles, JM. :
Hypertrophic osteodystrophy in the Weimaraner dog: lack of association between DQA1 alleles of the canine MHC and hypertrophic osteodystrophy. Vet J 171:308-13, 2006. Pubmed reference: 16490714. DOI: 10.1016/j.tvjl.2004.11.015.
2002 Gilad, J., Barnea, E., Klement, E. :
Aspirin treatment of postvaccinal hypertrophic osteodystrophy in a weimaraner puppy Veterinary Record 150:456, 2002. Pubmed reference: 11993985.
LaFond, E., Breur, G.J., Austin, C.C. :
Breed susceptibility for developmental orthopedic diseases in dogs Journal of the American Animal Hospital Association 38:467-477, 2002. Pubmed reference: 12220032.
1999 Abeles, V., Harrus, S., Angles, J.M., Shalev, G., Aizenberg, I., Peres, Y., Aroch, I. :
Hypertrophic osteodystrophy in six weimaraner puppies associated with systemic signs Veterinary Record 145:130-134, 1999. Pubmed reference: 10466830.
1983 Alexander, J.W. :
Selected skeletal dysplasias: craniomandibular osteopathy, multiple cartilaginous exostoses, and hypertrophic osteodystrophy. Vet Clin North Am Small Anim Pract 13:55-70, 1983. Pubmed reference: 6346655. DOI: 10.1016/s0195-5616(83)50004-1.
1982 Woodard, J.C. :
Canine hypertrophic osteodystrophy, a study of the spontaneous disease in littermates Veterinary Pathology 19:337-354, 1982. Pubmed reference: 6806967.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 17 Sep 2021