OMIA:000901-9925 : XX difference of sexual development, generic in Capra hircus (goat)

In other species: common carp , guppy , Japanese medaka , dog , domestic cat , horse , pig , llama

Categories: Reproductive system phene

Links to MONDO diseases:

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: This phene includes information about XX differences of sexual development (XX DSD) in animals with an XX karyotype for which the causal variant has so far not been identified. This phene has been renamed from 'XX testicular DSD (Disorder of Sexual Development)' [29/09/2023] and was previously known as Sex reversal: XX male or SRY-negative XX sex reversal.

Species-specific name: Polled/Intersex syndrome

Species-specific description: See also OMIA:000483-9925 : Polled/Horns in Capra hircus for more inforamtion on the polled/intersex syndrome (PIS).

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000901-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2002 Pailhoux, E., Vigier, B., Vaiman, D., Servel, N., Chaffaux, S., Cribiu, E.P., Cotinot, C. :
Ontogenesis of female-to-male sex-reversal in XX polled goats Developmental Dynamics 224:39-50, 2002. Pubmed reference: 11984872. DOI: 10.1002/dvdy.10083.
1998 Flores, J.M., Sanchez, M.A., Gonzalez, M., Pizarro, M. :
Caprine testicular hypoplasia associated with sexual reversion decreases the expression of insulin-like growth factor ii (igf-ii) mrna in testes Animal Reproduction Science 52:279-288, 1998. Pubmed reference: 9821502.
1996 Vaiman, D., Koutita, O., Oustry, A., Elsen, J.M., Manfredi, E., Fellous, M., Cribiu, E.P. :
Genetic mapping of the autosomal region involved in XX sex-reversal and horn development in goats Mammalian Genome 7:133-137, 1996. Pubmed reference: 8835530.
1994 Just, W., De Almeida, C.C., Goldshmidt, B., Vogel, W. :
The male pseudohermaphrodite XX polled goat is Zfy and Sry negative. Hereditas 120:71-5, 1994. Pubmed reference: 8206787. DOI: 10.1111/j.1601-5223.1994.00071.x.
Pailhoux, E., Cribiu, E.P., Chaffaux, S., Darre, R., Fellous, M., Cotinot, C. :
Molecular analysis of 60,XX pseudohermaphrodite polled goats for the presence of SRY and ZFY genes. J Reprod Fertil 100:491-6, 1994. Pubmed reference: 8021868. DOI: 10.1530/jrf.0.1000491.
1992 Karras, S., Modransky, P., Welker, B. :
Surgical correction of urethral dilatation in an intersex goat. J Am Vet Med Assoc 201:1584-6, 1992. Pubmed reference: 1289340.
K├Ânig, H., Elmiger, B., Stranzinger, G. :
[Intersexuality in hornless XX-goats: pathological findings in 2 young pseudobucks, 3 young bucks with urethral diverticula and 2 pseudohermaphroditic kids]. Schweiz Arch Tierheilkd 134:175-82, 1992. Pubmed reference: 1609259.
1990 Vallenzasca, C., Galli, A. :
Cytogenetical and histopathologic study of 2 cases of polled goats. Andrologia 22:289-290, 1990. Pubmed reference: 2240625.
1987 Rodrigues, M.T., Espeschit, C.J.B. :
[Hornlessness and the incidence of intersexuality in goats] Informe Agropecuaria 13:12-16, 1987.
1985 Bacalhau, A.S., Souza, W.H., Rodrigues, A., Pant, K.P. :
[Polledness as a factor affecting intersexuality in German Fawn kids in Paraiba] Revista Brasileira de Reproducao Animal 9:35-39, 1985.
1981 Ricordeau, G., Sanchez, G.F.F :
[Changes in the frequencies of horned animals in four types of French goat] Annales de Genetique et de Selection Animale 13:353-362, 1981.
1979 Guanti, G., De Benedictis, G., Minoia, P., Zarrilli, A. :
XX male syndrome in Maltese goats Acta Medica Veterinaria 25:63-70, 1979.
1969 Basrur, P.K. :
Some thoughts on the association of polled trait and intersexuality in goats Annales de Genetique et de Selection Animale 1:439-446, 1969.
Lauvergne, J.J. :
Progress in genetic knowledge of intersexuality associated with polledness in the goat of Alpine origin. Annales de Genetique et de Selection Animale 1:403-412, 1969.
1962 Laor, M., Barnea, R., Angel, H., Soller, M. :
Polledness and hermaphroditism in Saanen goats. Israel Journal of Agricultural Research 12:83-88, 1962.
1961 Dejong, S. :
[Is there a relationship between the horned condition in goats and the production of intersexes, male infertility and disturbed sex ratio?] Tijdschrift voor Diergeneeskunde 86:58-59, 1961.
1960 Dejong, S. :
[Is there a relationship between the horned condition in goats and the production of intersexes, male infertility and disturbed sex ratio?] Geitehouder 23:40 only, 1960.

Edit History


  • Created by Frank Nicholas on 16 Jul 2005
  • Changed by Imke Tammen2 on 01 Oct 2023