OMIA 000955-9031 : Sudden death in Gallus gallus

In other species: dog , horse

Category: Mortality / aging (incl. embryonic lethal)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific symbol: SDS

Markers: Basaki et al. (2016) "concluded that susceptibility to fatal cardiac arrhythmia in SDS may be associated with changes in intracellular Ca(2+) balance due to mutation and downregulation of chCASQ2" but did not provide any compelling evidence for a likely causal variant.

Baskai et al. (2019) "described for the first time five mutations (W2287S, T2368A, N2383I, P2425R, and P2436L) in the central region of chRYR2 (between amino acids 2239 and 2530) in relation to SDS" but presented no association results.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year. > > > > > > > > > >
2021 Wang, M.S., Zhang, J.J., Guo, X., Li, M., Meyer, R., Ashari, H., Zheng, Z.Q., Wang, S., Peng, M.S., Jiang, Y., Thakur, M., Suwannapoom, C., Esmailizadeh, A., Hirimuthugoda, N.Y., Zein, M.S.A., Kusza, S., Kharrati-Koopaee, H., Zeng, L., Wang, Y.M., Yin, T.T., Yang, M.M., Li, M.L., Lu, X.M., Lasagna, E., Ceccobelli, S., Gunwardana, H.G.T.N., Senasig, T.M., Feng, S.H., Zhang, H., Bhuiyan, A.K.F.H., Khan, M.S., Silva, G.L.L.P., Thuy, L.T., Mwai, O.A., Ibrahim, M.N.M., Zhang, G., Qu, K.X., Hanotte, O., Shapiro, B., Bosse, M., Wu, D.D., Han, J.L., Zhang, Y.P. :
Large-scale genomic analysis reveals the genetic cost of chicken domestication. BMC Biol 19:118, 2021. Pubmed reference: 34130700. DOI: 10.1186/s12915-021-01052-x.
2019 Basaki, M., Tabandeh, M.R., Aminlari, M., Asasi, K., Mohsenifard, E., Abdi-Hachesoo, B. :
Sequence and expression analysis of cardiac ryanodine receptor 2 in broilers that died from sudden death syndrome. Avian Pathol 48:444-453, 2019. Pubmed reference: 31081346. DOI: 10.1080/03079457.2019.1618439.
2016 Basaki, M., Asasi, K., Tabandeh, M.R., Aminlari, M. :
Polymorphism identification and cardiac gene expression analysis of the calsequestrin 2 gene in broiler chickens with sudden death syndrome. Br Poult Sci 57:151-60, 2016. Pubmed reference: 26953612. DOI: 10.1080/00071668.2015.1099615.
2009 Scorza, F.A., de Albuquerque, R., Arida, R.M., Schmidt, B., de Almeida, A.C., Scorza, C.A., Cavalheiro, E.A. :
Could sudden death syndrome (SDS) in chickens (Gallus gallus) be a valid animal model for sudden unexpected death in epilepsy (SUDEP)? Med Hypotheses 73:67-9, 2009. Pubmed reference: 19264421. DOI: 10.1016/j.mehy.2008.10.035.
2008 Olkowski, A.A., Wojnarowicz, C., Nain, S., Ling, B., Alcorn, J.M., Laarveld, B. :
A study on pathogenesis of sudden death syndrome in broiler chickens. Res Vet Sci 85:131-40, 2008. Pubmed reference: 17904171. DOI: 10.1016/j.rvsc.2007.08.006.
2005 Moghadam, H.K., McMillan, I., Chambers, J.R., Julian, R.J., Tranchant, C.C. :
Heritability of sudden death syndrome and its associated correlations to ascites and body weight in broilers. Br Poult Sci 46:54-7, 2005. Pubmed reference: 15835252. DOI: 10.1080/00071660400023862.
1998 Maxwell, M.H., Robertson, G.W. :
Uk survey of broiler ascites and sudden death syndromes in 1993 British Poultry Science 39:203-215, 1998. Pubmed reference: 9649872. DOI: 10.1080/00071669889132.
1996 White, H.B. :
Sudden death of chicken embryos with hereditary riboflavin deficiency. J Nutr 126:1303S-7S, 1996. Pubmed reference: 8642476. DOI: 10.1093/jn/126.suppl_4.1303S.
1994 Grashorn, M. :
Investigations on the Aetiology and Pathology of Sudden Death Syndrome in Meat-Type Chicken Archiv Fur Geflugelkunde 58:243-244, 1994.
1982 Whitehead, C.C., Randall, C.J. :
Interrelationships between biotin, choline and other B-vitamins and the occurrence of fatty liver and kidney syndrome and sudden death syndrome in broiler chickens. Br J Nutr 48:177-84, 1982. Pubmed reference: 7104288.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 24 May 2019