OMIA:000961-9940 : Copper deficiency, susceptibility to in Ovis aries (sheep) |
Categories: Homeostasis / metabolism phene
Single-gene trait/disorder: unknown
Disease-related: yes
Cross-species summary: Incoordination progressing to paralysis, blindness and death, associated with a deficiency of copper, which causes dysmyelination of the nerve cells in the brain and spinal cord. This phene was renamed from 'Swayback' to 'Copper deficiency, susceptibility to' [21/10/2022]
Species-specific name: Swayback, sway back
Species-specific description: This disorder is due to a deficiency of copper in the diet. There is substantial genetic variation in ability to withstand a copper deficiency, and hence in resistance to swayback (Wiener, 1966).
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:000961-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2024 | Adeniyi, O.O., Lenstra, J.A., Mastrangelo, S., Lühken, G. : |
Genome-wide comparative analyses for selection signatures indicate candidate genes for between-breed variability in copper accretion in sheep. Animal 18:S1751-7311(24)00266-0:101329, 2024. Pubmed reference: 39378609. DOI: 10.1016/j.animal.2024.101329. | |
1997 | Muylle, E. : |
Sway back in lambs [Dutch] Vlaams Diergeneeskundig Tijdschrift 66:141, 1997. | |
1996 | Alleyne, T., Adogwa, A., Lalla, A., Joseph, J., John, R. : |
Novel mitochondrial proteins and decreased intrinsic activity of cytochrome-c oxidase - characteristics of swayback disease in sheep Molecular & Chemical Neuropathology 28:285-293, 1996. | |
1972 | Kavanagh, P.J., Purcell, D.A., Thompson, R.H. : |
Congenital and delayed swayback in lambs in Northern Ireland Veterinary Record 90:538-540, 1972. Pubmed reference: 5073594. | |
1966 | Wiener, G., Field, A.C. : |
Blood copper levels in sheep in relation to genetic factors, parity and previous swayback history Nature 209:835-836, 1966. Pubmed reference: 5950873. | |
Wiener, G. : | |
Genetic and other factors in the occurrence of swayback in sheep Journal of Comparative Pathology 76:435-447, 1966. Pubmed reference: 6008381. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Imke Tammen2 on 21 Oct 2022