OMIA 000961-9940 : Swayback in Ovis aries |
Mendelian trait/disorder:
unknown
Considered a defect:
yes
Cross-species summary:
Incoordination progressing to paralysis, blindness and death, associated with a deficiency of copper, which causes dysmyelination of the nerve cells in the brain and spinal cord.
Species-specific description:
This disorder is due to a deficiency of copper in the diet. There is substantial genetic variation in ability to withstand a copper deficiency, and hence in resistance to swayback (Wiener, 1966).
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 1997 | Muylle, E. : | |
| Sway back in lambs [Dutch] Vlaams Diergeneeskundig Tijdschrift 66:141, 1997. | ||
| 1996 | Alleyne, T., Adogwa, A., Lalla, A., Joseph, J., John, R. : | |
| Novel mitochondrial proteins and decreased intrinsic activity of cytochrome-c oxidase - characteristics of swayback disease in sheep Molecular & Chemical Neuropathology 28:285-293, 1996. | ||
| 1972 | Kavanagh, P.J., Purcell, D.A., Thompson, R.H. : | |
| Congenital and delayed swayback in lambs in Northern Ireland Veterinary Record 90:538-540, 1972. Pubmed reference: 5073594. | ||
| 1966 | Wiener, G., Field, A.C. : | |
| Blood copper levels in sheep in relation to genetic factors, parity and previous swayback history Nature 209:835-836, 1966. Pubmed reference: 5950873. | ||
| Wiener, G. : | ||
| Genetic and other factors in the occurrence of swayback in sheep Journal of Comparative Pathology 76:435-447, 1966. Pubmed reference: 6008381. |
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- Created by Frank Nicholas on 06 Sep 2005