OMIA:001014-9615 : Transitional lumbosacral vertebrae in Canis lupus familiaris (dog)

In other species: domestic cat

Categories: Skeleton phene (incl. short stature & teeth)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Also known as Transitional vertebral segments

Species-specific symbol: TLSV

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breeds: Chihuahua (Dog) (VBO_0200338), German Shepherd Dog (Dog) (VBO_0200577), Labrador Retriever (Dog) (VBO_0200800).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:001014-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Estevam, M.V., Toniollo, G.H., Apparicio, M. :
The most common congenital malformations in dogs: Literature review and practical guide. Res Vet Sci 171:S0034-5288(24)00096-1:105230, 2024. Pubmed reference: 38492280. DOI: 10.1016/j.rvsc.2024.105230.
2023 Berg, J.A., Sævik, B.K., Lingaas, F., Trangerud, C. :
Lumbosacral transitional vertebra in 14 dog breeds in Norway: Occurrence, risk factors and association with hip dysplasia. Vet J 303:S1090-0233(23)00107-7:106056, 2023. Pubmed reference: 38092176. DOI: 10.1016/j.tvjl.2023.106056.
2021 Gluding, D., Stock, K.F., Tellhelm, B., Kramer, M., Eley, N. :
Genetic background of lumbosacral transitional vertebrae in German shepherd dogs. J Small Anim Pract 62:967-972, 2021. Pubmed reference: 34155659. DOI: 10.1111/jsap.13380.
2017 Flückiger, M.A., Steffen, F., Hässig, M., Morgan, J.P. :
Asymmetrical lumbosacral transitional vertebrae in dogs may promote asymmetrical hip joint development. Vet Comp Orthop Traumatol , 2017. Pubmed reference: 28094414. DOI: 10.3415/VCOT-16-05-0072.
Moeser, C.F., Wade, C.M. :
Relationship between transitional lumbosacral vertebrae and eight lumbar vertebrae in a breeding colony of Labrador Retrievers and Labrador Crosses. Aust Vet J 95:33-36, 2017. Pubmed reference: 28124426. DOI: 10.1111/avj.12547.
2015 Komsta, R., Łojszczyk-Szczepaniak, A., Dębiak, P. :
Lumbosacral transitional vertebrae, canine hip dysplasia, and sacroiliac joint degenerative changes on ventrodorsal radiographs of the pelvis in police working German shepherd dogs. Top Companion Anim Med 30:10-5, 2015. Pubmed reference: 26041591. DOI: 10.1053/j.tcam.2015.02.005.
2012 Lappalainen, A.K., Salomaa, R., Junnila, J., Snellman, M., Laitinen-Vapaavuori, O. :
Alternative classification and screening protocol for transitional lumbosacral vertebra in German shepherd dogs. Acta Vet Scand 54:27, 2012. Pubmed reference: 22549019. DOI: 10.1186/1751-0147-54-27.
2009 Flückiger, M., Geissbühler, U., Lang, J. :
[Lumbosacral transitional vertebrae: what is their impact on the health of affected dogs?]. Schweiz Arch Tierheilkd 151:133-5, 2009. Pubmed reference: 19263383. DOI: 10.1024/0036-7281.151.3.133.
2006 Damur-Djuric, N., Steffen, F., Hässig, M., Morgan, J.P., Flückiger, M.A. :
Lumbosacral transitional vertebrae in dogs: classification, prevalence, and association with sacroiliac morphology. Vet Radiol Ultrasound 47:32-8, 2006. Pubmed reference: 16429982.
Flückiger, M.A., Damur-Djuric, N., Hässig, M., Morgan, J.P., Steffen, F. :
A lumbosacral transitional vertebra in the dog predisposes to cauda equina syndrome. Vet Radiol Ultrasound 47:39-44, 2006. Pubmed reference: 16429983.
2003 Breit, S., Knaus, I., Künzel, W. :
Differentiation between lumbosacral transitional vertebrae, pseudolumbarisation, and lumbosacral osteophyte formation in ventrodorsal radiographs of the canine pelvis. Vet J 165:36-42, 2003. Pubmed reference: 12618068.
2002 Breit, S., Künzel, W. :
The diameter of the vertebral canal in dogs in cases of lumbosacral transitional vertebrae or numerical vertebral variations. Anat Embryol (Berl) 205:125-33, 2002. Pubmed reference: 12021914. DOI: 10.1007/s00429-002-0234-0.
2000 Jones, J.C., Inzana, K.D. :
Subclinical CT abnormalities in the lumbosacral spine of older large-breed dogs. Vet Radiol Ultrasound 41:19-26, 2000. Pubmed reference: 10695875.
1999 Morgan, J.P., Wind, A., Davidson, A.P. :
Bone dysplasias in the Labrador retriever: A radiographic study Journal of the American Animal Hospital Association 35:332-340, 1999. Pubmed reference: 10416779.
1995 Schultz, V.A., Watson, A.G. :
Lumbosacral transitional vertebra and thoracic limb malformations in a Chihuahua puppy. J Am Anim Hosp Assoc 31:101-6, 1995. Pubmed reference: 7773755. DOI: 10.5326/15473317-31-2-101.
1993 Morgan, J.P., Bahr, A., Franti, C.E., Bailey, C.S. :
Lumbosacral Transitional Vertebrae as a Predisposing Cause of Cauda Equina Syndrome in German Shepherd Dogs - 161 Cases (1987-1990) Journal of the American Veterinary Medical Association 202:1877-1882, 1993. Pubmed reference: 8320160.
1986 Winkler, W., Loeffler, K. :
[Lumbosacral transitional vertebrae in the dog]. Berl Munch Tierarztl Wochenschr 99:343-6, 1986. Pubmed reference: 3790061.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 30 Jan 2017
  • Changed by Imke Tammen2 on 25 Jun 2021