You are here: OMIA / Search / OMIA:001055 / horse

OMIA:001055-9796 : Vitiligo in Equus caballus (horse)

In other species: chicken , Rhesus monkey , dog , domestic cat , Northern giraffe , taurine cattle , water buffalo

Categories: Integument (skin) phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 193200 (trait) , 221350 (trait) , 270750 (trait) , 277465 (trait)

Mendelian trait/disorder: unknown

Disease-related: yes

Mapping: Druml et al. (2021) "performed a GWAS analysis using high-density 670 k single nucleotide polymorphism (SNP) data from 152 Lipizzan and 104 Noriker horses, which were phenotyped for vitiligo-like depigmentation by visual inspection. ... We identified seven candidate genes on four chromosomes (ECA1, ECA13, ECA17, ECA20) putatively involved in vitiligo pathogenesis in grey horses."

Breed: Purebred Spanish (Horse) (VBO_0001056).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:001055-9796: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Durward-Akhurst, S.A., Marlowe, J.L., Schaefer, R.J., Springer, K., Grantham, B., Carey, W.K., Bellone, R.R., Mickelson, J.R., McCue, M.E. :
Predicted genetic burden and frequency of phenotype-associated variants in the horse. Sci Rep 14:8396, 2024. Pubmed reference: 38600096. DOI: 10.1038/s41598-024-57872-8.
Giri, P., Desai, D., Dwivedi, M. :
Animal models unraveling the complexity of vitiligo pathogenesis. Autoimmun Rev 23:103515, 2024. Pubmed reference: 38185189. DOI: 10.1016/j.autrev.2024.103515.
Laseca, N., Molina, A., Perdomo-González, D., Ziadi, C., Azor, P.J., Valera, M. :
Exploring the genetic landscape of vitiligo in the Pura Raza Español horse: A genomic perspective. Animals (Basel) 14:2420, 2024. Pubmed reference: 39199954. DOI: 10.3390/ani14162420.
2021 Druml, T., Brem, G., Velie, B., Lindgren, G., Horna, M., Ricard, A., Grilz-Seger, G. :
Equine vitiligo-like depigmentation in grey horses is related to genes involved in immune response and tumor metastasis. BMC Vet Res 17:336, 2021. Pubmed reference: 34696794. DOI: 10.1186/s12917-021-03046-x.
2019 Sánchez-Guerrero, M.J., Solé, M., Azor, P.J., Sölkner, J., Valera, M. :
Genetic and environmental risk factors for vitiligo and melanoma in Pura Raza Español horses. Equine Vet J 51:606-611, 2019. Pubmed reference: 30624804. DOI: 10.1111/evj.13067.
Tham, H.L., Linder, K.E., Olivry, T. :
Autoimmune diseases affecting skin melanocytes in dogs, cats and horses: vitiligo and the uveodermatological syndrome: a comprehensive review. BMC Vet Res 15:251, 2019. Pubmed reference: 31324191. DOI: 10.1186/s12917-019-2003-9.
1986 Naughton, G.K., Mahaffey, M., Bystryn, J.C. :
Antibodies to surface antigens of pigmented cells in animals with vitiligo. Proc Soc Exp Biol Med 181:423-6, 1986. Pubmed reference: 3511476. DOI: 10.3181/00379727-181-42275.
1965 Meijer, W.C. :
Dermatological diagnosis in horse and cattle judging. Vet Rec 77:1046-7, 1965. Pubmed reference: 5890084. DOI: 10.1136/vr.77.36.1046.
1962 Meijer, W.C.P. :
Vitiligo in seven horses and five cattle Tijdschrift voor Diergeneeskunde 87:411-425, 1962.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 25 Nov 2011
  • Changed by Imke Tammen2 on 28 Aug 2021
  • Changed by Imke Tammen2 on 02 Nov 2021
  • Changed by Imke Tammen2 on 03 Sep 2024