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OMIA 001055-9796 : Vitiligo in Equus caballus

In other species: dog , chicken , water buffalo , cattle , domestic cat

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 193200 (trait) , 221350 (trait) , 270750 (trait) , 277465 (trait)

Mendelian trait/disorder: unknown

Considered a defect: yes

Mapping: Druml et al. (2021) "performed a GWAS analysis using high-density 670 k single nucleotide polymorphism (SNP) data from 152 Lipizzan and 104 Noriker horses, which were phenotyped for vitiligo-like depigmentation by visual inspection. ... We identified seven candidate genes on four chromosomes (ECA1, ECA13, ECA17, ECA20) putatively involved in vitiligo pathogenesis in grey horses."

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Druml, T., Brem, G., Velie, B., Lindgren, G., Horna, M., Ricard, A., Grilz-Seger, G. :
Equine vitiligo-like depigmentation in grey horses is related to genes involved in immune response and tumor metastasis. BMC Vet Res 17:336, 2021. Pubmed reference: 34696794. DOI: 10.1186/s12917-021-03046-x.
2019 Sánchez-Guerrero, M.J., Solé, M., Azor, P.J., Sölkner, J., Valera, M. :
Genetic and environmental risk factors for vitiligo and melanoma in Pura Raza Español horses. Equine Vet J 51:606-611, 2019. Pubmed reference: 30624804. DOI: 10.1111/evj.13067.
Tham, H.L., Linder, K.E., Olivry, T. :
Autoimmune diseases affecting skin melanocytes in dogs, cats and horses: vitiligo and the uveodermatological syndrome: a comprehensive review. BMC Vet Res 15:251, 2019. Pubmed reference: 31324191. DOI: 10.1186/s12917-019-2003-9.
1986 Naughton, G.K., Mahaffey, M., Bystryn, J.C. :
Antibodies to surface antigens of pigmented cells in animals with vitiligo. Proc Soc Exp Biol Med 181:423-6, 1986. Pubmed reference: 3511476. DOI: 10.3181/00379727-181-42275.
1965 Meijer, W.C. :
Dermatological diagnosis in horse and cattle judging. Vet Rec 77:1046-7, 1965. Pubmed reference: 5890084. DOI: 10.1136/vr.77.36.1046.
1962 Meijer, W.C.P. :
Vitiligo in seven horses and five cattle Tijdschrift voor Diergeneeskunde 87:411-425, 1962.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 25 Nov 2011
  • Changed by Imke Tammen2 on 28 Aug 2021
  • Changed by Imke Tammen2 on 02 Nov 2021