OMIA 001079-9913 : Yellow fat in Bos taurus
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|BCO2||beta-carotene oxygenase 2||Bos taurus||15||NC_037342.1 (22513065..22580770)||BCO2||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|Holstein||Yellow fat||BCO2||nonsense (stop-gain)||ARS-UCD1.2||15||g.22552375G>A||c.306G>A||p.(W102*)||UMD3.1 position is g.22877552G>A; cDNA position is based on XM_024975217.1||rs109226280||2009||19398771||Variant information kindly provided or confirmed by Hubert Pausch, including information from Additional Table 6 of Jansen et al. (2013) BMC Genomics201314:446 https://doi.org/10.1186/1471-2164-14-446. The genomic location on ARS-UCD1.2 was determined by Katie Eager and Shernae Woolley, EMAI, NSW. Department of Primary Industries.|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2012||Tian, R., Cullen, N.G., Morris, C.A., Fisher, P.J., Pitchford, W.S., Bottema, C.D. :|
|Major effect of retinal short-chain dehydrogenase reductase (RDHE2) on bovine fat colour. Mamm Genome 23:378-86, 2012. Pubmed reference: 22451137. DOI: 10.1007/s00335-012-9396-0.|
|2010||Tian, R., Pitchford, W.S., Morris, C.A., Cullen, N.G., Bottema, C.D. :|
|Genetic variation in the beta, beta-carotene-9', 10'-dioxygenase gene and association with fat colour in bovine adipose tissue and milk. Anim Genet 41:253-9, 2010. Pubmed reference: 19968649. DOI: 10.1111/j.1365-2052.2009.01990.x.|
|2009||Berry, SD., Davis, SR., Beattie, EM., Thomas, NL., Burrett, AK., Ward, HE., Stanfield, AM., Biswas, M., Ankersmit-Udy, AE., Oxley, PE., Barnett, JL., Pearson, JF., van der Does, Y., Macgibbon, AH., Spelman, RJ., Lehnert, K., Snell, RG. :|
|Mutation in bovine beta-carotene oxygenase 2 affects milk color. Genetics 182:923-6, 2009. Pubmed reference: 19398771. DOI: 10.1534/genetics.109.101741.|
- Created by Frank Nicholas on 03 Sep 2010
- Changed by Frank Nicholas on 14 Sep 2011
- Changed by Frank Nicholas on 09 Dec 2011