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OMIA:001130-9615 : Leukodystrophy, generic in Canis lupus familiaris (dog)

In other species: sheep , American mink

Categories: Nervous system phene

Mendelian trait/disorder: unknown

Considered a defect: yes

Key variant is published: no

Species-specific name: Dalmatian leukodystrophy; miniature poodle demyelination

Species-specific description: Information about canine spongiform leukoencephalomyelopathy or Shetland Sheepdog leukodystrophy in Shetland Sheepdogs and Australian cattle dogs due to mutations in the mitochondrial CYTB gene have been moved to 'OMIA:002684-9615 : Leukodystrophy, CYTB-related in Canis lupus familiaris'. Other forms of leukodystrophy exist and have separate entries. [3/5/2023]

Breeds: Dalmatian (Dog) (VBO_0200427), Poodle, Miniature (Dog) (VBO_0201051), Scottish Terrier (Dog) (VBO_0201198).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001130-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1987 Sorjonen, D.C., Cox, N.R., Kwapien, R.P. :
Myeloencephalopathy with eosinophilic refractile bodies (Rosenthal fibers) in a Scottish terrier. J Am Vet Med Assoc 190:1004-6, 1987. Pubmed reference: 3570949.
1977 Averill, D.R., Bronson, R.T. :
Inherited necrotizing myelopathy of Afghan Hounds. J Neuropathol Exp Neurol 36:734-47, 1977. Pubmed reference: 886368. DOI: 10.1097/00005072-197707000-00008.
Bjerkas, I. :
Hereditary 'cavitating' leucodystrophy in Dalmatian dogs: light and electron microscopic studies Acta Neuropathologia 40:163-169, 1977.
1961 Douglas, S.W., Palmer, A.C. :
Idiopathic demyelination of brain-stem and spinal cord in a Miniature Poodle puppy J Pathol Bacteriol 82:67-71, 1961. Pubmed reference: 13724072. DOI: 10.1002/path.1700820109.

Edit History


  • Created by Frank Nicholas on 12 Jun 2006
  • Changed by Frank Nicholas on 28 Sep 2011
  • Changed by Frank Nicholas on 12 Dec 2011
  • Changed by Frank Nicholas on 05 Dec 2012
  • Changed by Tosso Leeb on 29 May 2013
  • Changed by Frank Nicholas on 04 Nov 2020
  • Changed by Imke Tammen2 on 16 Jan 2023
  • Changed by Imke Tammen2 on 03 May 2023