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OMIA 001181-9796 : Atrial fibrillation in Equus caballus

In other species: dog

Possibly relevant human trait(s) and/or gene(s) (MIM number): 194200 (trait)

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: yes

Key variant known: no

Inheritance: Physick-Sheard et al. (2014) concluded that atrial fibrillation (AF) in Standardbreds is multifactorial and reported that "Heritability of AF on the underlying scale (h²(u)) was estimated at 29.6 ± 3.9% and on the observed binomial scale (h²(o)), at 9.6%."

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Decloedt, A., Van Steenkiste, G., Vera, L., Buhl, R., van Loon, G. :
Atrial fibrillation in horses Part 2: Diagnosis, treatment and prognosis. Vet J 268:105594, 2021. Pubmed reference: 33468306. DOI: 10.1016/j.tvjl.2020.105594.
2020 Decloedt, A., Van Steenkiste, G., Vera, L., Buhl, R., van Loon, G. :
Atrial fibrillation in horses part 1: Pathophysiology. Vet J 263:105521, 2020. Pubmed reference: 32928494. DOI: 10.1016/j.tvjl.2020.105521.
Schüttler, D., Bapat, A., Kääb, S., Lee, K., Tomsits, P., Clauss, S., Hucker, W.J. :
Animal Models of Atrial Fibrillation. Circ Res 127:91-110, 2020. Pubmed reference: 32716814. DOI: 10.1161/CIRCRESAHA.120.316366.
2018 Kraus, M., Physick-Sheard, P., Brito, L.F., Sargolzaei, M., Schenkel, F.S. :
Marginal ancestral contributions to atrial fibrillation in the Standardbred racehorse: Comparison of cases and controls. PLoS One 13:e0197137, 2018. Pubmed reference: 29763439. DOI: 10.1371/journal.pone.0197137.
2016 Navas de Solís, C., Reef, V.B., Slack, J., Jose-Cunilleras, E. :
Evaluation of coagulation and fibrinolysis in horses with atrial fibrillation. J Am Vet Med Assoc 248:201-6, 2016. Pubmed reference: 26720087. DOI: 10.2460/javma.248.2.201.
2014 Physick-Sheard, P., Kraus, M., Basrur, P., McGurrin, K., Kenney, D., Schenkel, F. :
Breed predisposition and heritability of atrial fibrillation in the Standardbred horse: a retrospective case-control study. J Vet Cardiol 16:173-84, 2014. Pubmed reference: 25087649. DOI: 10.1016/j.jvc.2014.03.006.
2009 Jesty, S.A., Kraus, M.S., Kraus, M., Gelzer, A.R., Gelzer, A., Rishniw, M., Moise, N.S., Moïse, N.S. :
Effect of transvenous electrical cardioversion on plasma cardiac troponin I concentrations in horses with atrial fibrillation. J Vet Intern Med 23:1103-7, 2009. Pubmed reference: 19678887. DOI: 10.1111/j.1939-1676.2009.0369.x.
2003 Ohmura, H., Hiraga, A., Takahashi, T., Kai, M., Jones, J.H. :
Risk factors for atrial fibrillation during racing in slow-finishing horses Journal of the American Veterinary Medical Association 223:84-8, 2003. Pubmed reference: 12839069.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 16 Apr 2015
  • Changed by Imke Tammen2 on 16 Sep 2021