OMIA:001187-9615 : Hypospadias in Canis lupus familiaris (dog)
Categories: Renal / urinary system phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 146450 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Developmental abnormality in which the urethra of males opens on the underside of the penis or on the perineum.
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2020||Chang, J., Wang, S., Zheng, Z. :|
|Etiology of hypospadias: A comparative review of genetic factors and developmental processes between human and animal models. Res Rep Urol 12:673-686, 2020. Pubmed reference: 33381468. DOI: 10.2147/RRU.S276141.|
|2019||Krzemińska, P., D'Anza, E., Ciotola, F., Paciello, O., Restucci, B., Peretti, V., Albarella, S., Switonski, M. :|
|Polymorphisms of MAMLD1, SRD5A2, and AR candidate genes in seven dogs (78,XY; SRY-Positive) affected by hypospadias or cryptorchidism. Sex Dev 13:92-98, 2019. Pubmed reference: 31055572. DOI: 10.1159/000500219.|
|2012||Switonski, M., Payan-Carreira, R., Bartz, M., Nowacka-Woszuk, J., Szczerbal, I., Colaço, B., Pires, M.A., Ochota, M., Nizanski, W. :|
|Hypospadias in a male (78,XY; SRY-positive) dog and sex reversal female (78,XX; SRY-negative) dogs: clinical, histological and genetic studies. Sex Dev 6:128-34, 2012. Pubmed reference: 21893969. DOI: 10.1159/000330921.|
- Created by Frank Nicholas on 06 Oct 2011