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OMIA:001187-9615 : Hypospadias in Canis lupus familiaris (dog)

In other species: horse , taurine cattle , goat , sheep , mule

Categories: Renal / urinary system phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 146450 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Developmental abnormality in which the urethra of males opens on the underside of the penis or on the perineum.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2011). OMIA:001187-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2020 Chang, J., Wang, S., Zheng, Z. :
Etiology of hypospadias: A comparative review of genetic factors and developmental processes between human and animal models. Res Rep Urol 12:673-686, 2020. Pubmed reference: 33381468. DOI: 10.2147/RRU.S276141.
2019 Krzemińska, P., D'Anza, E., Ciotola, F., Paciello, O., Restucci, B., Peretti, V., Albarella, S., Switonski, M. :
Polymorphisms of MAMLD1, SRD5A2, and AR candidate genes in seven dogs (78,XY; SRY-Positive) affected by hypospadias or cryptorchidism. Sex Dev 13:92-98, 2019. Pubmed reference: 31055572. DOI: 10.1159/000500219.
2012 Switonski, M., Payan-Carreira, R., Bartz, M., Nowacka-Woszuk, J., Szczerbal, I., Colaço, B., Pires, M.A., Ochota, M., Nizanski, W. :
Hypospadias in a male (78,XY; SRY-positive) dog and sex reversal female (78,XX; SRY-negative) dogs: clinical, histological and genetic studies. Sex Dev 6:128-34, 2012. Pubmed reference: 21893969. DOI: 10.1159/000330921.

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  • Created by Frank Nicholas on 06 Oct 2011