OMIA:001191-9615 : Hemivertebrae in Canis lupus familiaris |
In other species: cattle , goat
Categories: Skeleton phene (incl. short stature & teeth)
Possibly relevant human trait(s) and/or gene(s) (MIM number): 207620 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: no
Mode of inheritance: Multifactorial
Considered a defect: yes
Key variant known: no
Inheritance: As reported by Schlensker and Distl (2015), "Heritability estimates for the number and grade of hemivertebrae were 0.58 and 0.53, respectively. The number of coccygeal vertebrae showed a heritability estimate of 0.35. In addition, the number of coccygeal vertebrae was negatively correlated with the number and grade of hemivertebrae. The prevalence of hemivertebrae could increase if dogs with shorter tails are preferentially selected for breeding purposes."
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2019 | Wyatt, S.E., Lafuente, P., Ter Haar, G., Packer, R.M.A., Smith, H., De Decker, S. : |
| Gait analysis in French bulldogs with and without vertebral kyphosis. Vet J 244:45-50, 2019. Pubmed reference: 30825894 . DOI: 10.1016/j.tvjl.2018.12.008. | |
| 2015 | Schlensker, E., Distl, O. : |
| Heritability of hemivertebrae in the French bulldog using an animal threshold model. Vet J :, 2015. Pubmed reference: 26626092 . DOI: 10.1016/j.tvjl.2015.10.044. | |
| 2014 | Charalambous, M., Jeffery, N.D., Smith, P.M., Goncalves, R., Barker, A., Hayes, G., Ives, E., Vanhaesebrouck, A.E. : |
| Surgical treatment of dorsal hemivertebrae associated with kyphosis by spinal segmental stabilisation, with or without decompression. Vet J 202:267-73, 2014. Pubmed reference: 25241946 . DOI: 10.1016/j.tvjl.2014.08.011. | |
| 2007 | Jeffery, N.D., Smith, P.M., Talbot, C.E. : |
| Imaging findings and surgical treatment of hemivertebrae in three dogs. J Am Vet Med Assoc 230:532-6, 2007. Pubmed reference: 17302550 . DOI: 10.2460/javma.230.4.532. | |
| 2005 | Besalti, O., Ozak, A., Pekcan, Z., Eminaga, S. : |
| Nasca classification of hemivertebra in five dogs. Ir Vet J 58:688-90, 2005. Pubmed reference: 21851666 . DOI: 10.1186/2046-0481-58-12-688. | |
| 1992 | Bailey, C.S., Morgan, J.P. : |
| Congenital spinal malformations. Vet Clin North Am Small Anim Pract 22:985-1015, 1992. Pubmed reference: 1641930 . | |
| 1989 | Kirberger, RM. : |
| Congenital malformation and variation of the lumbar vertebrae in a dog. 60:111-2, 1989. Pubmed reference: 2607532 . | |
| 1982 | Kramer, JW., Schiffer, SP., Sande, RD., Rantanen, NW., Whitener, EK. : |
| Characterization of heritable thoracic hemivertebra of the German shorthaired pointer. 181:814-5, 1982. Pubmed reference: 7141980 . | |
| 1980 | Widmer, W.R. : |
| Sublaxated hemivertebrae at T5, with spinal cord compression. J Am Vet Med Assoc 176:1017-8, 1980. Pubmed reference: 7380715 . | |
| 1975 | Done, S.H., Drew, R.A., Robins, G.M., Lane, J.G. : |
| Hemivertebra in the dog: clinical and pathological observations Veterinary Record 96:313-317, 1975. Pubmed reference: 1129930 . | |
| 1969 | Grenn, H.H., Lindo, D.E. : |
| Hemivertebrae with severe kypho-scoliosis and accompanying deformities in a dog. Can Vet J 10:214-6, 1969. Pubmed reference: 5388275 . |
Edit History
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 30 Dec 2015