OMIA:001203-9615 : Budd-chiari syndrome in Canis lupus familiaris (dog)

In other species: domestic cat

Categories: Cardiovascular system phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 600880 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: obstruction of hepatic venous outflow

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breeds: Cavalier King Charles Spaniel (Dog) (VBO_0200309), King Charles Spaniel (Dog) (VBO_0200765).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:001203-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2015 Wrzosek, M., Płonek, M., Nicpoń, J., Cizinauskas, S., Pakozdy, A. :
Retrospective multicenter evaluation of the "fly-catching syndrome" in 24 dogs: EEG, BAER, MRI, CSF findings and response to antiepileptic and antidepressant treatment. Epilepsy Behav 53:184-9, 2015. Pubmed reference: 26584225. DOI: 10.1016/j.yebeh.2015.10.013.
2013 Driver, C.J., Chandler, K., Walmsley, G., Shihab, N., Volk, H.A. :
The association between Chiari-like malformation, ventriculomegaly and seizures in cavalier King Charles spaniels. Vet J 195:235-7, 2013. Pubmed reference: 22749114. DOI: 10.1016/j.tvjl.2012.05.014.
Penderis, J. :
Chiari-like malformation: a substantive health and welfare problem in the Cavalier King Charles spaniel. Vet J 195:133-4, 2013. Pubmed reference: 23041179. DOI: 10.1016/j.tvjl.2012.08.026.
2009 Schlicksup, MD., Weisse, CW., Berent, AC., Solomon, JA. :
Use of endovascular stents in three dogs with Budd-Chiari syndrome. J Am Vet Med Assoc 235:544-50, 2009. Pubmed reference: 19719445. DOI: 10.2460/javma.235.5.544.
2003 Lu, D., Lamb, C.R., Pfeiffer, D.U., Targett, M.P. :
Neurological signs and results of magnetic resonance imaging in 40 cavalier King Charles spaniels with Chiari type 1-like malformations Veterinary Record 153:260-3, 2003. Pubmed reference: 12974337.
2001 Schoeman, J.P., Stidworthy, M.F. :
Budd-Chiari-like syndrome associated with an adrenal phaeochromocytoma in a dog Journal of Small Animal Practice 42:191-194, 2001. Pubmed reference: 11327667.
2000 Bynevelt, M., Rusbridge, C., Britton, J. :
Dorsal dens angulation and a Chiari type malformation in a Cavalier King Charles spaniel Veterinary Radiology & Ultrasound 41:521-524, 2000. Pubmed reference: 11130793.
1998 Fine, D.M., Olivier, N.B., Walshaw, R., Schall, W.D. :
Surgical correction of late-onset Budd-Chiari-like syndrome in a dog. J Am Vet Med Assoc 212:835-7, 1998. Pubmed reference: 9530422.
1990 Otto, C.M., Mahaffey, M., Jacobs, C., Binhazim, A. :
Cor Triatrium Dexter with Budd-Chiari Syndrome and a Review of Ascites in Young Dogs Journal of Small Animal Practice 31:385-389, 1990.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 23 Oct 2022