OMIA 001246-9615 : Chronic valvular disease in Canis lupus familiaris

Mendelian trait/disorder: unknown

Considered a defect: yes

Associated genes:

Symbol Description Species Chr Location OMIA gene details page Other Links
THRB thyroid hormone receptor, beta Canis lupus familiaris 23 NC_006605.3 (19278650..19648547) THRB Homologene, Ensembl, NCBI gene
THR thyroid hormone receptor beta1 Canis lupus familiaris - no genomic information (-..-) THR Homologene, Ensembl, NCBI gene
THRA thyroid hormone receptor, alpha Canis lupus familiaris 9 NC_006591.3 (22493445..22469466) THRA Homologene, Ensembl, NCBI gene


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2000 Karlstam, E., Haggstrom, J., Kvart, C., Jonsson, L., Michaelsson, M. :
Pulmonary artery lesions in cavalier King Charles spaniels Veterinary Record 147:166-167, 2000. Pubmed reference: 10975336.
1999 Shahrara, S., Tidholm, A., Drvota, V., Haggstom, J., Sylven, C. :
Upregulation of thyroid hormone receptor beta(1) and beta(2) messenger RNA in the myocardium of dogs with dilated cardiomyopathy or chronic valvular disease American Journal of Veterinary Research 60:848-852, 1999. Pubmed reference: 10407478.
1996 Swenson, L., Haggstrom, J., Kvart, C., Juneja, R.K. :
Relationship between parental cardiac status in Cavalier King Charles spaniels and prevalence and severity of chronic valvular disease in offspring Journal of the American Veterinary Medical Association 208:2009 ff., 1996.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005