OMIA:001256-9823 : Woolly hair in Sus scrofa (pig)
Categories: Integument (skin) phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Species-specific name: Curly coat or Curly hair
Inheritance: Schachler et al. (2020) reported that "analysis of two matings of Mangalitza with straight-coated pig breeds confirmed an autosomal dominant inheritance of curly hair" and that "These results contrast with previous predictions from crossings of Mangalitza with Cornwall, Middle White and Large White, which suggested an intermediary hair type for F1-piglets". The actual mode of inheritance, therefore, within the Mangalitza breed, and in other breeds, still remains to be determined.
Markers: Schachler et al. (2020) "suggest that more than one variant is causative for the specific hair type of Mangalitza pigs."
Have human generated variants been created, e.g. through genetic engineering and gene editing
Canastrão, Brazil (Pig) (VBO_0012718),
Mangalitsa (Pig) (VBO_0001169).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2023||Khaveh, N., Schachler, K., Berghöfer, J., Jung, K., Metzger, J. :|
|Altered hair root gene expression profiles highlight calcium signaling and lipid metabolism pathways to be associated with curly hair initiation and maintenance in Mangalitza pigs. Front Genet 14:1184015, 2023. Pubmed reference: 37351343. DOI: 10.3389/fgene.2023.1184015.|
|2020||Schachler, K., Distl, O., Metzger, J. :|
|Tracing selection signatures in the pig genome gives evidence for selective pressures on a unique curly hair phenotype in Mangalitza. Sci Rep 10:22142, 2020. Pubmed reference: 33335158. DOI: 10.1038/s41598-020-79037-z.|
|2016||Leroy, G., Besbes, B., Boettcher, P., Hoffmann, I., Capitan, A., Baumung, R. :|
|Rare phenotypes in domestic animals: unique resources for multiple applications. Anim Genet 47:141-53, 2016. Pubmed reference: 26662214. DOI: 10.1111/age.12393.|
|1982||Ollivier, L., Sellier, P. :|
|Pig genetics: a review Annales de Genetique et de Selection Animale 14:481-544, 1982.|
|1934||Rhoad, A.O. :|
|Woolly hair in swine Journal of Heredity 25:371-375, 1934.|
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 20 Dec 2020