OMIA:001278-9823 : Hypotrichosis, dominant in Sus scrofa (pig) |
In other species: golden hamster
Categories: Integument (skin) phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 146520 (trait) , 146550 (trait) , 183849 (trait) , 211370 (trait) , 203655 (trait) , 246500 (trait) , 250460 (trait) , 278200 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Considered a defect: yes
Key variant known: no
Cross-species summary: Dominant form of hair loss.
Inheritance: Meyer and Drommer (1968) provided convincing evidence of autosomal dominant inheritance of hairlessness. It seems very likely that the causative mutation is at a different locus from that which gives rise to "Hypotrichosis, recessive" (MIA 000540) in pigs. However, breeding trials to test non-allelism have not been reported.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:001278-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 1968 | Meyer, H., Drommer, W. : |
| Inherited hypotrichosis in pigs Deutsche Tierarztliche Wochenschrift 75:13-18, 1968. Pubmed reference: 5691394. | |
| 1918 | Hart, E.B., Steenbock, H. : |
| Thyroid hyperplasia and the relation of iodine to the hairless pig malady Journal of Biological Chemistry 33:313-323, 1918. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005