OMIA:001278-9823 : Hypotrichosis, dominant in Sus scrofa (pig)
In other species: golden hamster
Categories: Integument (skin) phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Considered a defect: yes
Key variant known: no
Cross-species summary: Dominant form of hair loss.
Inheritance: Meyer and Drommer (1968) provided convincing evidence of autosomal dominant inheritance of hairlessness. It seems very likely that the causative mutation is at a different locus from that which gives rise to "Hypotrichosis, recessive" (MIA 000540) in pigs. However, breeding trials to test non-allelism have not been reported.
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|1968||Meyer, H., Drommer, W. :|
|Inherited hypotrichosis in pigs Deutsche Tierarztliche Wochenschrift 75:13-18, 1968. Pubmed reference: 5691394.|
|1918||Hart, E.B., Steenbock, H. :|
|Thyroid hyperplasia and the relation of iodine to the hairless pig malady Journal of Biological Chemistry 33:313-323, 1918.|
- Created by Frank Nicholas on 06 Sep 2005