OMIA 001278-9823 : Hypotrichosis, dominant in Sus scrofa

In other species: golden hamster

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 146520 , 146550 , 183849 , 211370 , 203655 , 246500 , 250460 , 278200

Mendelian trait/disorder: yes

Considered a defect: yes

Key variant known: no

Cross-species summary: Dominant form of hair loss.

Inheritance: Meyer and Drommer (1968) provided convincing evidence of autosomal dominant inheritance of hairlessness. It seems very likely that the causative mutation is at a different locus from that which gives rise to "Hypotrichosis, recessive" (MIA 000540) in pigs. However, breeding trials to test non-allelism have not been reported.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
1968 Meyer, H., Drommer, W. :
Inherited hypotrichosis in pigs Deutsche Tierarztliche Wochenschrift 75:13-18, 1968. Pubmed reference: 5691394.
1918 Hart, E.B., Steenbock, H. :
Thyroid hyperplasia and the relation of iodine to the hairless pig malady Journal of Biological Chemistry 33:313-323, 1918.

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  • Created by Frank Nicholas on 06 Sep 2005