OMIA 001287-9615 : Keratitis in Canis lupus familiaris

In other species: horse

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 148190 , 148200 , 148210 , 242150

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Dominant

Considered a defect: yes

Key variant known: no

Species-specific name: Chronic superficial keratitis

Species-specific symbol: CSK

Inheritance: Cheng et al. (2016): "evidence strongly suggests that CSK [in Greyhounds] is inherited as a simple Mendelian trait with dominant inheritance and should be amenable to gene mapping".

Breed: Greyhound.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2016 Cheng, S., Wigney, D., Haase, B., Wade, C.M. :
Inheritance of chronic superficial keratitis in Australian Greyhounds. Anim Genet 47:629, 2016. Pubmed reference: 27147552. DOI: 10.1111/age.12446.
2011 Jokinen, P., Rusanen, E.M., Kennedy, L.J., Lohi, H. :
MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs. Vet Immunol Immunopathol 140:37-41, 2011. Pubmed reference: 21144596. DOI: 10.1016/j.vetimm.2010.11.007.
2007 Lynch, G.L. :
Ophthalmic examination findings in a group of retired racing Greyhounds. Vet Ophthalmol 10:363-7, 2007. Pubmed reference: 17970997. DOI: 10.1111/j.1463-5224.2007.00570.x.
1996 Clerc, B., Jegou, J.P. :
Superficial punctate keratitis Canine Practice 21:6-11, 1996.
1977 Slatter, D.H., Lavach, J.D., Severin, G.A., Young, S. :
Uberreiter's syndrome (chronic superficial keratitis) in dogs in the Rocky Mountain area--a study of 463 cases. J Small Anim Pract 18:757-72, 1977. Pubmed reference: 599907.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 02 Jun 2016
  • Changed by Frank Nicholas on 07 Sep 2016