OMIA 001287-9615 : Keratitis in Canis lupus familiaris

In other species: horse

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 148190 (trait) , 148200 (trait) , 148210 (trait) , 242150 (trait)

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Dominant

Considered a defect: yes

Key variant known: no

Species-specific name: Chronic superficial keratitis

Species-specific symbol: CSK

Inheritance: Cheng et al. (2016): "evidence strongly suggests that CSK [in Greyhounds] is inherited as a simple Mendelian trait with dominant inheritance and should be amenable to gene mapping".

Breed: Greyhound.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2016 Cheng, S., Wigney, D., Haase, B., Wade, C.M. :
Inheritance of chronic superficial keratitis in Australian Greyhounds. Anim Genet 47:629, 2016. Pubmed reference: 27147552. DOI: 10.1111/age.12446.
2014 Drahovska, Z., Balicki, I., Trbolova, A., Mihalova, M., Holickova, M. :
A retrospective study of the occurrence of chronic superficial keratitis in 308 German Shepherd dogs: 1999-2010. Pol J Vet Sci 17:543-6, 2014. Pubmed reference: 25286670. DOI: 10.2478/pjvs-2014-0082.
2013 Barrientos, L.S., Zapata, G., Crespi, J.A., Posik, D.M., Díaz, S., It, V., Peral-García, P., Giovambattista, G. :
A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLA-DQA1. Vet Immunol Immunopathol 156:205-10, 2013. Pubmed reference: 24238945. DOI: 10.1016/j.vetimm.2013.10.009.
2011 Jokinen, P., Rusanen, E.M., Kennedy, L.J., Lohi, H. :
MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs. Vet Immunol Immunopathol 140:37-41, 2011. Pubmed reference: 21144596. DOI: 10.1016/j.vetimm.2010.11.007.
2008 Mashhady Rafie, S., Mousavi, G. :
A case report of atypic chronic superficial keratitis (pannus) in a sheepdog. Asian Journal of Animal and Veterinary Advances 3:386-389, 2008. DOI: 10.3923/ajava.2008.386.389.
2007 Lynch, G.L. :
Ophthalmic examination findings in a group of retired racing Greyhounds. Vet Ophthalmol 10:363-7, 2007. Pubmed reference: 17970997. DOI: 10.1111/j.1463-5224.2007.00570.x.
2005 Williams, D.L. :
Major histocompatibility class II expression in the normal canine cornea and in canine chronic superficial keratitis. Vet Ophthalmol 8:395-400, 2005. Pubmed reference: 16359362. DOI: 10.1111/j.1463-5224.2005.00412.x.
1996 Clerc, B., Jegou, J.P. :
Superficial punctate keratitis Canine Practice 21:6-11, 1996.
1994 Chavkin, M.J., Roberts, S.M., Salman, M.D., Severin, G.A., Scholten, N.J. :
Risk factors for development of chronic superficial keratitis in dogs. J Am Vet Med Assoc 204:1630-4, 1994. Pubmed reference: 8050943.
1977 Slatter, D.H., Lavach, J.D., Severin, G.A., Young, S. :
Uberreiter's syndrome (chronic superficial keratitis) in dogs in the Rocky Mountain area--a study of 463 cases. J Small Anim Pract 18:757-72, 1977. Pubmed reference: 599907.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 02 Jun 2016
  • Changed by Frank Nicholas on 07 Sep 2016