OMIA 001435-93934 : Feather colour, extended brown in Coturnix japonica

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Incompletely Dominant

Considered a defect: no

Key variant known: yes

Year key variant first reported: 2006

Species-specific symbol: E

Molecular basis: Nadeau et al. (2006) showed that this feather colour is due to missense mutation in the MC1R gene: "a G-to-A substitution leading to a Glu92Lys mutation . . . is likely to be the causative mutation for the increased melanism in [the] Extended brown" feather-colour phenotype.

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
MC1R Coturnix japonica - no genomic information (-..-) MC1R Ensembl

Variants

By default, variants are sorted chronologically by year of publication, to provide a historical perspective.

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Breed(s) Variant Phenotype Gene Allele Type of Variant Reference Sequence Chr. g. or m. c. or n. p. Verbal Description EVA ID Year Published PubMed ID(s) Acknowledgements
Feather colour, extended brown MC1R missense c.?G>A p.E92K 2006 16734695

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2017 Gluckman, T.L., Mundy, N.I. :
The differential expression of MC1R regulators in dorsal and ventral quail plumages during embryogenesis: Implications for plumage pattern formation. PLoS One 12:e0174714, 2017. Pubmed reference: 28355309. DOI: 10.1371/journal.pone.0174714.
2013 Zhang, X.H., Pang, Y.Z., Zhao, S.J., Xu, H.W., Li, Y.L., Xu, Y., Guo, Z., Wang, D.D. :
The relationship of plumage colours with MC1R (Melanocortin 1 Receptor) and ASIP (Agouti Signaling Protein) in Japanese quail (Coturnix coturnix japonica). Br Poult Sci 54:306-11, 2013. Pubmed reference: 23639082. DOI: 10.1080/00071668.2013.780122.
2009 Minvielle, F., Cecchi, T., Passamonti, P., Gourichon, D., Renieri, C. :
Plumage colour mutations and melanins in the feathers of the Japanese quail: a first comparison. Anim Genet 40:971-4, 2009. Pubmed reference: 19496774. DOI: 10.1111/j.1365-2052.2009.01929.x.
2006 Nadeau, NJ., Minvielle, F., Mundy, NI. :
Association of a Glu92Lys substitution in MC1R with extended brown in Japanese quail (Coturnix japonica). Anim Genet 37:287-9, 2006. Pubmed reference: 16734695. DOI: 10.1111/j.1365-2052.2006.01442.x.

Edit History


  • Created by Frank Nicholas on 22 Oct 2008
  • Changed by Frank Nicholas on 08 Sep 2011
  • Changed by Frank Nicholas on 12 Sep 2011
  • Changed by Frank Nicholas on 12 Oct 2011
  • Changed by Frank Nicholas on 09 Dec 2011
  • Changed by Frank Nicholas on 21 Mar 2012
  • Changed by Frank Nicholas on 31 Mar 2017