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OMIA 001468-9615 : Multiple system degeneration in Canis lupus familiaris

Possibly relevant human trait(s) and/or gene(s) (MIM number): 146500 (trait)

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Key variant known: no

Species-specific name: Canine multiple system degeneration

Species-specific symbol: CMSD

Mapping: O'Brien et al. (2005) mapped this disorder to a 15Mb region of chromosome CFA1

Breeds: Chinese Crested Dog, Ibizan Hound, Kerry Blue Terrier.

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2022 St Jean, S.C., Jortner, B.S., Doan, R.N., Dindot, S.V., Johnson, G.S., Bullock, G., Whitley, D.B., Levine, J.M., Hancock, S.K., Ambrus, A., Porter, B.F. :
Pathologic characterization of canine multiple system degeneration in the Ibizan hound. Vet Pathol 59:132-137, 2022. Pubmed reference: 34490804. DOI: 10.1177/03009858211043088.
2005 O'Brien, DP., Johnson, GS., Schnabel, RD., Khan, S., Coates, JR., Johnson, GC., Taylor, JF. :
Genetic mapping of canine multiple system degeneration and ectodermal dysplasia loci. J Hered 96:727-34, 2005. Pubmed reference: 15958791. DOI: 10.1093/jhered/esi086.
1976 Delahunta, A. :
Hereditary cerebellar cortical and extrapyramidal nuclear abiotrophy in Kerry Blue Terriers. Proceedings of the Twentieth World Veterinary Congress, Thessaloniki 1:120-128, 1976.
1946 Metler, FA, Goss, LJ :
Canine chorea due to striatocerebellar degeneration of unknown etiology. J Am Vet Med Assoc 108:377–384, 1946.

Edit History


  • Created by Frank Nicholas on 21 Jun 2009
  • Changed by Imke Tammen2 on 12 Feb 2022