OMIA:001499-9615 : Aggression in Canis lupus familiaris (dog)
In other species: pig
Categories: Behaviour / neurological phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: no
Mode of inheritance: Multifactorial
Considered a defect: yes
Key variant known: no
Mapping: Våge et al. (2010) genotyped "50 aggressive and 81 non-aggressive dogs" for 62 SNPs in or close to 16 candidate (neurotransmitter-related) genes, and "Allelic associations with aggression were identified for DRD1, HTR1D, HTR2C and SLC6A1".
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
|2010||Vage, J., Wade, C., Biagi, T., Fatjo, J., Amat, M., Lindblad-Toh, K., Lingaas, F. :|
|Association of dopamine- and serotonin-related genes with canine aggression. Genes Brain Behav 9:372-8, 2010. Pubmed reference: 20132314. DOI: 10.1111/j.1601-183X.2010.00568.x.|
- Created by Frank Nicholas on 24 Aug 2010
- Changed by Frank Nicholas on 21 May 2013