OMIA 001499-9615 : Aggression in Canis lupus familiaris

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: yes

Key variant known: no

Mapping: VĂ¥ge et al. (2010) genotyped "50 aggressive and 81 non-aggressive dogs" for 62 SNPs in or close to 16 candidate (neurotransmitter-related) genes, and "Allelic associations with aggression were identified for DRD1, HTR1D, HTR2C and SLC6A1".

Reference


2010 Vage, J., Wade, C., Biagi, T., Fatjo, J., Amat, M., Lindblad-Toh, K., Lingaas, F. :
Association of dopamine- and serotonin-related genes with canine aggression. Genes Brain Behav 9:372-8, 2010. Pubmed reference: 20132314. DOI: 10.1111/j.1601-183X.2010.00568.x.

Edit History


  • Created by Frank Nicholas on 24 Aug 2010
  • Changed by Frank Nicholas on 21 May 2013