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OMIA:001499-9615 : Aggression in Canis lupus familiaris (dog)

In other species: pig

Categories: Behaviour / neurological phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: yes

Key variant known: no

Mapping: Våge et al. (2010) genotyped "50 aggressive and 81 non-aggressive dogs" for 62 SNPs in or close to 16 candidate (neurotransmitter-related) genes, and "Allelic associations with aggression were identified for DRD1, HTR1D, HTR2C and SLC6A1".

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2013). OMIA:001499-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2010 Vage, J., Wade, C., Biagi, T., Fatjo, J., Amat, M., Lindblad-Toh, K., Lingaas, F. :
Association of dopamine- and serotonin-related genes with canine aggression. Genes Brain Behav 9:372-8, 2010. Pubmed reference: 20132314. DOI: 10.1111/j.1601-183X.2010.00568.x.

Edit History


  • Created by Frank Nicholas on 24 Aug 2010
  • Changed by Frank Nicholas on 21 May 2013