OMIA 001516-9615 : Gastrointestinal stromal tumor in Canis lupus familiaris

Possibly relevant human trait(s) and/or gene(s) (MIM number): 606764

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal

Considered a defect: yes

Key variant known: yes

Year key variant first reported: 2010

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog Canis lupus familiaris 13 NC_006595.3 (47108442..47190935) KIT Homologene, Ensembl, NCBI gene

Variants

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Breed(s) Variant Phenotype Gene Allele Type of Variant Reference Sequence Chr. g. or m. c. or n. p. Verbal Description EVA ID Year Published PubMed ID(s) Acknowledgements
Gastrointestinal stromal tumor KIT deletion, small (<=20) NC_006595.2 g.50110838_50110843delAGTGGA 2010 20950418
Gastrointestinal stromal tumor KIT deletion, small (<=20) NC_006595.2 g.50110841_50110846delGGAAGG 2010 20950418

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2016 Takanosu, M., Amano, S., Kagawa, Y. :
Analysis of c-KIT exon 11 mutations in canine gastrointestinal stromal tumours. Vet J 207:118-23, 2016. Pubmed reference: 26631948. DOI: 10.1016/j.tvjl.2015.10.051.
2010 Gregory-Bryson, E., Bartlett, E., Kiupel, M., Hayes, S., Yuzbasiyan-Gurkan, V. :
Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11. BMC Cancer 10:559, 2010. Pubmed reference: 20950418. DOI: 10.1186/1471-2407-10-559.

Edit History


  • Created by Frank Nicholas on 02 Nov 2010
  • Changed by Frank Nicholas on 12 Dec 2011