OMIA:001519-9615 : Persistent hyaloid remnants in Canis lupus familiaris (dog)

Categories: Vision / eye phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific name: Persistent hyaloid artery (PHA)

Species-specific description: Genetics Committee of the American College of Veterinary Opthalmologists (2021): "congenital defect resulting from abnormalities in the development and regression of the hyaloid artery. The blood vessel remnant can be present in the vitreous as a small patent vascular strand (PHA) or as a non-vascular strand that appears gray-white (persistent hyaloid remnant)"

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: Australian Shepherd (Dog) (VBO_0200095).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001519-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2021 Genetics Committee of the American College of Veterinary Opthalmologists :
The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition , 2021.
2007 Munyard, KA., Sherry, CR., Sherry, L. :
A retrospective evaluation of congenital ocular defects in Australian Shepherd dogs in Australia. Vet Ophthalmol 10:19-22, 2007. Pubmed reference: 17204124. DOI: 10.1111/j.1463-5224.2007.00486.x.

Edit History

  • Created by Frank Nicholas on 02 Nov 2010
  • Changed by Imke Tammen2 on 23 Oct 2022
  • Changed by Imke Tammen2 on 17 Jun 2023