OMIA 001573-9615 : Leukemia, chronic monocytic in Canis lupus familiaris
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|BCR||breakpoint cluster region||Canis lupus familiaris||26||NC_006608.3 (27856280..27980923)||BCR||Homologene, Ensembl, NCBI gene|
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Mixed breed||Leukemia, chronic monocytic||BCR||complex rearrangement||"Philadelphia chromosome" - a chromosomal translocation that results in chronic leukemia. This translocation involves the gene known as breakpoint cluster region (BCR).||2011||21143615|
|2011||Cruz Cardona, JA., Milner, R., Alleman, AR., Williams, C., Vernau, W., Breen, M., Tompkins, M. :|
|BCR-ABL translocation in a dog with chronic monocytic leukemia. Vet Clin Pathol 40:40-7, 2011. Pubmed reference: 21143615. DOI: 10.1111/j.1939-165X.2010.00277.x.|
- Created by Frank Nicholas on 12 Jul 2011
- Changed by Frank Nicholas on 28 Sep 2011
- Changed by Frank Nicholas on 12 Dec 2011