OMIA 001580-9685 : Feet, white (gloving) in Felis catus
This variant was published by Montague et al. (2014).Prevalence: Montague et al. (2014): "Genotyping these [two adjacent KIT] SNPs in a larger sample including 150 Birman cats and 729 additional cats confirmed that all Birman cats were homozygous for both SNPs and that all first-generation outcrossed Birman cats with no gloving were carriers of the polymorphisms". Associated gene:
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|KIT||v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog||Felis catus||B1||NC_018726.3 (164039337..163952966)||KIT||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Birman||Gloving||KIT||g||delins, small (<=20)||FelCat5||B1||c.1035_1036delinsCA||p.Glu345Asp,His346Asn||Montague et al. (2014) describe this variant as "two adjacent missense mutations".||2010||21147473|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2014||Montague, M.J., Li, G., Gandolfi, B., Khan, R., Aken, B.L., Searle, S.M., Minx, P., Hillier, L.W., Koboldt, D.C., Davis, B.W., Driscoll, C.A., Barr, C.S., Blackistone, K., Quilez, J., Lorente-Galdos, B., Marques-Bonet, T., Alkan, C., Thomas, G.W., Hahn, M.W., Menotti-Raymond, M., O'Brien, S.J., Wilson, R.K., Lyons, L.A., Murphy, W.J., Warren, W.C. :|
|Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication. Proc Natl Acad Sci U S A 111:17230-5, 2014. Pubmed reference: 25385592. DOI: 10.1073/pnas.1410083111.|
|2010||Lyons, LA. :|
|Feline genetics: clinical applications and genetic testing. Top Companion Anim Med 25:203-12, 2010. Pubmed reference: 21147473. DOI: 10.1053/j.tcam.2010.09.002.|
- Created by Frank Nicholas on 20 Jul 2011
- Changed by Frank Nicholas on 10 Sep 2011
- Changed by Frank Nicholas on 09 Dec 2011
- Changed by Frank Nicholas on 23 Nov 2012
- Changed by Frank Nicholas on 15 May 2020
- Changed by Frank Nicholas on 09 Jan 2021