OMIA:001589-9615 : Anal furunculosis in Canis lupus familiaris (dog)

Categories: Digestive / alimentary phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Genetic testing: The Kennel Club's list of genetic tests (http://www.thekennelclub.org.uk/download/8288/DNA-Tests-Worldwide-2.pdf) includes an indirect DNA test for this disorder, based on the MHC association reported by Kennedy et al. (2008).

Breed: German Shepherd Dog (Dog) (VBO_0200577).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2022). OMIA:001589-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2014 Massey, J., Short, A.D., Catchpole, B., House, A., Day, M.J., Lohi, H., Ollier, W.E., Kennedy, L.J. :
Genetics of canine anal furunculosis in the German shepherd dog. Immunogenetics 66:311-24, 2014. Pubmed reference: 24626934. DOI: 10.1007/s00251-014-0766-5.
2009 Barnes, A., O'Neill, T., Kennedy, LJ., Short, AD., Catchpole, B., House, A., Binns, M., Fretwell, N., Day, MJ., Ollier, WE. :
Association of canine anal furunculosis with TNFA is secondary to linkage disequilibrium with DLA-DRB1*. Tissue Antigens 73:218-24, 2009. Pubmed reference: 19254251. DOI: 10.1111/j.1399-0039.2008.01188.x.
House, AK., Binns, MM., Gregory, SP., Catchpole, B. :
Analysis of NOD1, NOD2, TLR1, TLR2, TLR4, TLR5, TLR6 and TLR9 genes in anal furunculosis of German shepherd dogs. Tissue Antigens 73:250-4, 2009. Pubmed reference: 19254256. DOI: 10.1111/j.1399-0039.2008.01190.x.
2008 Kennedy, L.J., O'Neill, T., House, A., Barnes, A., Kyöstilä, K., Innes, J., Fretwell, N., Day, M.J., Catchpole, B., Lohi, H., Ollier, W.E. :
Risk of anal furunculosis in German shepherd dogs is associated with the major histocompatibility complex. Tissue Antigens 71:51-6, 2008. Pubmed reference: 17999655. DOI: 10.1111/j.1399-0039.2007.00964.x.
Tivers, MS., Catchpole, B., Gregory, SP., House, AK. :
Interleukin-2 and interferon-gamma mRNA expression in canine anal furunculosis lesions and the effect of ciclosporin therapy. Vet Immunol Immunopathol 125:31-6, 2008. Pubmed reference: 18541310. DOI: 10.1016/j.vetimm.2008.04.018.
1988 Arnall, L. :
Anal furunculosis. Vet Rec 123:499-500, 1988. Pubmed reference: 3201701.
Burley, K.G. :
Anal furunculosis. Vet Rec 123:452, 1988. Pubmed reference: 3201692.
Frost, R.C. :
Anal furunculosis. Vet Rec 123:355, 1988. Pubmed reference: 3195021.
Turner, T. :
Anal furunculosis. Vet Rec 123:555, 1988. Pubmed reference: 3206811.
1980 Houlton, J.E. :
Anal furunculosis: a review of seventy cases. J Small Anim Pract 21:575-84, 1980. Pubmed reference: 7230744.
Houlton, J.E. :
Canine anal furunculosis: a modified approach. J Small Anim Pract 21:585-93, 1980. Pubmed reference: 7230745.
1973 Robins, G.M., Lane, J.G. :
The management of anal furunculosis. J Small Anim Pract 14:333-42, 1973. Pubmed reference: 4803921.

Edit History


  • Created by Frank Nicholas on 21 Jul 2011
  • Changed by Imke Tammen2 on 23 Oct 2022