OMIA 001601-9796 : Sex reversal: XY female, SRY-positive in Equus caballus
In other species: dog Mendelian trait/disorder: unknown Considered a defect: yes History: Raudsepp et al. (2010) reported five cases of this disorder. Molecular basis: Raudsepp et al. (2012) reported a "~300 kb deletion in two [affected] Standardbreds on ECA29 involving aldo-keto reductase gene cluster known to catalyze the conversion of sex hormones".
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2012||Raudsepp, T., Fang, E., Qu, Z., Gosch, S., Das, P.J., Arnold, C., McDonnell, S., Adelson, D.L., Chowdhary, B.P. :|
|Genomic Copy Number Variation in Horses with Disorders of Sexual Development Plant & Animal Genome (PAG) XX :Abstract W257, 2012.|
|2010||Raudsepp, T., Durkin, K., Lear, T.L., Das, P.J., Avila, F., Kachroo, P., Chowdhary, B.P. :|
|Molecular heterogeneity of XY sex reversal in horses. Anim Genet 41 Suppl 2:41-52, 2010. Pubmed reference: 21070275. DOI: 10.1111/j.1365-2052.2010.02101.x.|
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